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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


AmaWaterways Cruise Tours, AmaPrima Cruise Tours
AmaPrima Cruise Tours13 Night - Europe's Rivers & Castles (Wine Cruise) with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Rhine Gorge, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Apr 12, Aug 2, 2027: Mar 21, May 2, Jun 27, Aug 8, Sep 19, More...
AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Europe's Rivers & Castles (Wine Cruise)
Starting in Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Rhine Gorge, Lahnstein, Cochem, Wasserbillig, Luxembourg
2026 Sails: Apr 15, Aug 5, 2027: Mar 24, May 5, Jun 30, Aug 11, Sep 22, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Apr 19, Aug 9, 2027: Apr 20, Jun 15, Aug 10, Sep 7, Oct 5, More...
Viking River, Viking Baldur
Viking Baldur Cruises14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: Apr 19, May 17, Jun 14, Jul 12, Aug 9, Sep 6, Oct 4, Nov 1, More...
Viking River, Viking Magni
Viking Magni Cruises14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Apr 19, May 17, Jun 14, Jul 12, Aug 9, Sep 6, Oct 4, Nov 1, More...
Viking River, Viking Ve
Viking Ve Cruises14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: Apr 21, May 19, Jun 16, Jul 14, Aug 11, Sep 8, Oct 6, Nov 3, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises14 Night - Jewels of Europe
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Apr 22, May 20, Jun 17, Jul 15, Aug 12, Sep 9, Oct 7, 2027: Mar 12, Apr 23, May 21, Jun 18, Jul 16, Aug 13, Sep 10, Oct 8, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises7 Night - Charming Castles & Vineyards of the Rhine & Moselle
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Zurich
2026 Sails: Apr 22, Jul 1, Aug 5, Oct 7, 2027: May 5, Jul 21, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises11 Night - Charming Castles & Vineyards of the Rhine & Moselle with Switzerland
Starting in Frankfurt / Mainz, Koblenz, Bernkastel, Cochem, Rudesheim, Rastatt, Breisach, Basel / Montreux, Montreux, Montreux / Bern, Bern / Lucerne / Zurich, Zurich
2026 Sails: Apr 22, Jul 1, Aug 5, 2027: May 5, Jul 21, More...
Viking River, Viking Vidar
Viking Vidar Cruises14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Apr 22, Jun 3, Jul 15, Aug 26, Oct 7, 2027: Jun 2, Jul 14, Aug 25, Oct 6, More...

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Main River Cruises