Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

AmaWaterways, AmaSofia

14 Night - Magnificent Europe
Starting in Amsterdam, Dusseldorf, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 24, More...

Scenic Luxury, Scenic Jewel

23 Night - Jewels of Europe with Eastern Europe Explorer
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: May 25, Jul 20, More...

Amadeus River, MS Amadeus Cara

14 Night - Across Europe - Amsterdam to Budapest
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Emmersdorf, Vienna, Bratislava, Budapest
2026 Sails: May 28, More...

Amadeus River, MS Amadeus Cara

7 Night - Three-Rivers Cruise
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg
2026 Sails: May 28, More...

AmaWaterways Tours, AmaStella Tours

16 Night - Magnificent Europe (Smithsonian Journeys) with Amsterdam Pre-Cruise
Starting in Amsterdam, Cologne, Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 28, More...

Uniworld Tours, River Duchess Tours

23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: May 29, Aug 21, More...

AmaWaterways, AmaStella

14 Night - Magnificent Europe (Smithsonian Journeys)
Starting in Amsterdam, Cologne, Rudesheim, Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 30, More...

Avalon Waterways, Avalon Illumination

14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: May 30, Aug 1, Sep 26, 2027: Jun 29, Aug 22, More...

Viking River, Viking Baldur

14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: May 31, Jun 28, Jul 26, Aug 23, Sep 20, Oct 18, 2027: Apr 25, May 23, Jun 20, Jul 18, Aug 15, Sep 12, Oct 10, More...

Avalon Waterways, Avalon Impression

14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 2, Sep 29, 2027: May 28, Jul 21, Sep 13, More...

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