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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Riviera River Cruises, MS Oscar Wilde
MS Oscar Wilde Cruises14 Night - Cruise the Heart of Europe
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2027 Sails: May 4, More...
Viking River, Viking Skirnir
Viking Skirnir Cruises10 Night - Rhine & Main Explorer
Starting in Basel, Breisach, Strasbourg, Karlsruhe, Frankfurt, Scenic Sailing Main River, Marktheidenfeld, Wurzburg, Bamberg, Nuremberg
2027 Sails: May 4, More...
AmaWaterways, AmaCerto
AmaCerto Cruises7 Night - Medieval Treasures
Starting in Basel, Strasbourg, Ludwigshafen, Frankfurt, Miltenberg, Wertheim, Wurzburg, Eltmann, Nuremberg
2027 Sails: May 5, Jul 14, Aug 25, Oct 6, More...
Avalon Waterways Cruise Tours, Avalon Panorama Cruise Tours
Avalon Panorama Cruise Ship17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany / Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2027 Sails: May 5, May 19, Jun 2, Jun 16, Jun 30, Jul 28, Aug 11, Aug 25, Sep 8, More...
Scenic Luxury Cruises, Scenic Crystal
Scenic Crystal Cruises17 Night - Jewels of Europe with Paris
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Rhine Gorge / Rudesheim, Miltenberg to Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2027 Sails: May 5, More...
Avalon Waterways, Avalon Passion
Avalon Passion Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2027 Sails: May 6, Oct 16, More...
Avalon Waterways, Avalon Passion
Avalon Passion Cruises21 Night - Iconic Rivers of Europe - the Rhine, Main & Danube
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation)
2027 Sails: May 6, More...
Avalon Waterways Cruise Tours, Avalon Passion Cruise Tours
Avalon Passion Cruises22 Night - Iconic Rivers of Europe - the Rhine, Main & Danube with in Bucharest
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation) Bucharest, Bucharest
2027 Sails: May 6, More...
Avalon Waterways Cruise Tours, Avalon Passion Cruise Tours
Avalon Passion Cruises24 Night - Iconic Rivers of Europe - the Rhine, Main & Danube with in Bucharest and in Transylvania
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation) Bucharest, Brasov, Brasov / Sinaia / Bucharest, Bucharest
2027 Sails: May 6, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises17 Night - Jewels of Europe with London
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / London, London
2027 Sails: May 7, Jul 2, More...

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Main River Cruises