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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury Cruises, Scenic Jade
Scenic Jade17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2027 Sails: Jun 4, Jul 2, Aug 27, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II9 Night - Reflections On the Rhine (Southbound)
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2027 Sails: Jun 5, Jul 8, Aug 30, More...
Avalon Waterways Cruise Tours, Avalon Tranquility II Cruise Tours
Avalon Tranquility II Cruise Tours11 Night - Reflections On the Rhine with in Lucerne (Southbound)
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation) Swiss Alps, Lucerne
2027 Sails: Jun 5, Jul 8, Aug 30, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruise Tours14 Night - Swiss Splendors by Train with Romantic Rhine Cruise
Starting in Arrive in Lake Geneva, Switzerland, Lake Geneva, Lake Geneva / Zermatt / Gornergrat Excursion, Zermatt / Interlaken, Interlaken, Interlaken / Brienz / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2027 Sails: Jun 12, Jun 26, Aug 21, Sep 4, More...
Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2027 Sails: Jun 15, Jul 27, More...
Emerald Cruises, Emerald Astra
Emerald Astra20 Night - Prague & Splendours of Europe & Belgian Delights
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Brussels, Brussels
2027 Sails: Jun 16, More...
Emerald Cruises, Emerald Astra
Emerald Astra17 Night - Prague & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2027 Sails: Jun 16, More...
Viking River Cruise Tours, Viking Vidar Cruise Tours
Viking Vidar Cruise Tours22 Night - European Sojourn
Starting in Amsterdam, Kinderdijk, Scenic Sailing : Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing : Main River, Spessart, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing : Wachau Valley, Krems, Vienna, Budapest, Kalocsa, Osijek, Belgrade, Golubac, Scenic Sailing : the Iron Gates, Vidin, Ruse, Bucharest
2027 Sails: Jun 16, Jul 28, Sep 8, Oct 20, More...
Emerald Cruises, Emerald Sky
Emerald Sky17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2027 Sails: Jun 17, More...
Emerald Cruises, Emerald Astra
Emerald Astra17 Night - Splendours of Europe & Belgian Delights
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Brussels, Brussels
2027 Sails: Jun 19, More...

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Main River Cruises