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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Uniworld Boutique River Cruise Tours, S.S. Audrey Cruise Tours
S.S. Audrey Cruise Tours11 Night - Paris, Prague & Germany's Hidden Gems
Starting in Arrive in Prague, Transfer to Hotel, Prague, Prague, Transfer to Bamberg, Kitzingen, Volkach, Wertheim, Aschaffenburg (Heidelberg), Rudesheim, Cochem, Trier, Luxembourg, Trier, Paris, Paris, Depart Paris
2027 Sails: May 8, Jun 25, Jul 23, More...
Viking River, Viking Rota
Viking Rota Cruises14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2027 Sails: May 8, Jun 5, Jul 3, Jul 31, Aug 28, Sep 25, Oct 23, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises15 Night - Enchanted Europe (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg-excursion to Munich, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2027 Sails: May 11, Oct 30, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruises17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany / Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2027 Sails: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, More...
Riviera River Cruises, MS Riviera Resplendence
MS Riviera Resplendence Cruises14 Night - Cruise the Heart of Europe
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2027 Sails: May 12, Sep 1, More...
AmaWaterways Cruise Tours, AmaLea Cruise Tours
AmaLea Cruise Tours18 Night - Magnificent Europe with Amsterdam Pre-Cruise and Budapest Post-Cruise
Starting in Amsterdam, Dusseldorf, Cologne, Rudesheim, Wertheim, Wurzburg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2027 Sails: May 13, More...
Viking River, Viking Modi
Viking Modi Cruises10 Night - Rhine & Main Explorer
Starting in Basel, Breisach, Strasbourg, Karlsruhe, Frankfurt, Scenic Sailing Main River, Marktheidenfeld, Wurzburg, Bamberg, Nuremberg
2027 Sails: May 14, More...
AmaWaterways, AmaLea
AmaLea Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Dusseldorf, Cologne, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2027 Sails: May 15, Jun 12, More...
Emerald Cruises, Emerald Star
Emerald Star Cruises17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2027 Sails: May 15, Jul 24, Aug 21, Oct 16, More...
Riviera River Cruises, MS Riviera Radiance
MS Riviera Radiance Cruises14 Night - Cruise the Heart of Europe
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2027 Sails: May 16, More...

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Main River Cruises