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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Astra
Emerald Astra Cruises20 Night - Prague to Paris & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 29, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises17 Night - Prague & Christmas Markets of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Nov 29, 2027: Dec 3, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises9 Night - Christmastime from Nuremberg to Basel
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 1, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises5 Night - Christmastime in the Heart of Germany
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 1, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises9 Night - Christmastime from Basel to Nuremberg
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 2, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises15 Night - Christmastime from Basel to Vienna
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Excursion to Munich (Embarkation), Nuremberg, Regensburg, Passau, Melk, Austria, Vienna, Vienna (Disembarkation)
2026 Sails: Dec 2, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises4 Night - Christmastime in Alsace & Germany (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt (Disembarkation)
2026 Sails: Dec 2, More...
Avalon Waterways Cruise Tours, Avalon Tranquility II Cruise Tours
Avalon Tranquility II Cruises11 Night - Christmastime from Basel to Nuremberg with in Prague
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt Excursion to Rudesheim, Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 2, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises14 Night - Christmas Markets of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Dec 2, 2027: Dec 6, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises17 Night - Christmas Markets of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg / Kelheim, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Dec 2, More...

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Main River Cruises