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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises17 Night - Christmas Markets with Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Nov 24, 2027: Nov 23, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises14 Night - Christmas Markets
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Nov 24, 2027: Nov 23, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises14 Night - Christmas Markets of Europe
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Kelheim / Regensburg, Passau / Linz, Melk, Vienna, Bratislava, Budapest
2026 Sails: Nov 25, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises17 Night - Prague & Christmas Markets of Europe
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Kelheim / Regensburg, Passau / Linz, Melk, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Nov 25, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises17 Night - Christmas Markets with Paris
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 25, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises14 Night - Christmas Markets
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim, Cologne, Amsterdam
2026 Sails: Nov 25, More...
Uniworld Boutique River Cruise Collection, S.S. Elisabeth
S.S. Elisabeth Cruises7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Nov 25, Dec 9, More...
Avalon Waterways, Avalon Panorama
Avalon Panorama Cruise Ship4 Night - Christmastime in Alsace & Germany (Northbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Speyer, Germany / Heidelberg Excursion, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...
Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours
Avalon Imagery II Cruises11 Night - Christmastime from Nuremberg to Basel with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Nov 29, More...
Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours
Avalon Imagery II Cruises7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Nov 29, More...

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Main River Cruises