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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises28 Night - Romantic Rhine & Moselle with Wonders of Switzerland & Austria
Starting in Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Interlaken, Interlaken, Interlaken / Lucerne and Engelberg / Zurich, Zurich, Zurich / Basel, Breisach, Strasbourg, Mannheim, Rudesheim, Cochem, Bernkastel, Cruising Day, Koblenz, Dusseldorf, Arnhem, Antwerp, Bruinisse, Dordrecht, Amsterdam
2026 Sails: Sep 30, More...
Emerald Cruises, Emerald Star
Emerald Star Cruises17 Night - Splendours of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 3, 2027: May 1, Jun 26, Sep 4, Oct 30, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Oct 7, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises17 Night - Paris & Splendours of Europe
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 8, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises20 Night - Paris to Prague & Splendours of Europe
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Oct 8, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises28 Night - North Sea to the Black Sea with Turkey
Starting in Istanbul, Istanbul / Canakkale, Canakkale, Canakkale / Istanbul, Istanbul, Istanbul / Bucharest, Bucharest / Giurgiu, Silistra, Rouse, Cruising Day, Belgrade, Osijek, Mohacs / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Oct 13, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises22 Night - Black Sea to the North Sea
Starting in Bucharest, Bucharest / Giurgiu, Silistra, Rouse, Cruising Day, Belgrade, Osijek, Mohacs / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Oct 19, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Oct 28, 2027: Sep 1, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Oct 28, 2027: May 19, More...
Scenic Luxury Cruises, Scenic Amber
Scenic Amber Cruises20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Oct 30, 2027: May 7, More...

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Main River Cruises