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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Star
Emerald Star Cruises24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 23, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Sep 23, 2027: Jun 4, Jul 2, Aug 27, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises20 Night - Prague & Splendours of Europe & Belgian Delights
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Brussels, Brussels
2026 Sails: Sep 24, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises17 Night - Prague & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 24, 2027: Jul 1, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Sep 25, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises17 Night - Splendours of Europe & Belgian Delights
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Brussels, Brussels
2026 Sails: Sep 27, 2027: May 17, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 27, 2027: Feb 22, May 17, Jul 4, Nov 3, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises28 Night - North Sea to the Black Sea with Turkey
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Mohacs, Osijek, Belgrade, Cruising Day, Svishtov / Rousse, Silistra, Giurgiu / Bucharest, Istanbul, Istanbul / Canakkale, Canakkale, Canakkale / Istanbul, Istanbul
2026 Sails: Sep 29, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises22 Night - North Sea to the Black Sea
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Mohacs, Osijek, Belgrade, Cruising Day, Svishtov / Rousse, Silistra, Giurgiu / Bucharest, Bucharest
2026 Sails: Sep 29, More...
Riviera River Cruises, MS Riviera Resplendence
MS Riviera Resplendence Cruises10 Night - Rhine Cruise to Switzerland (Including Glacier Express Extension)
Starting in Zermatt, Switzerland, Davos, Switzerland, Basel, Switzerland, Rhine River, Speyer, Germany, Rudesheim, Germany, Koblenz, Germany, Rhine River, Cologne, Germany
2026 Sails: Sep 30, More...

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Main River Cruises