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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Avalon Waterways, Avalon Imagery II
Avalon Imagery II Cruises8 Night - German Grandeur for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg (Disembarkation)
2026 Sails: Oct 31, 2027: May 11, Oct 30, More...
Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours
Avalon Imagery II Cruises10 Night - German Grandeur with in Munich for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg (Disembarkation) Munich, Munich
2026 Sails: Oct 31, 2027: May 11, Oct 30, More...
Avalon Waterways Cruise Tours, Avalon Tranquility II Cruise Tours
Avalon Tranquility II Cruises17 Night - Enchanted Europe for Beer Enthusiasts with in Budapest (Westbound)
Starting in Budapest, Hungary, Budapest, Budapest (Embarkation), Vienna, Austria, Vienna, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Nuremberg-excursion to Munich, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Seligenstadt, Boppard, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Nov 2, More...
Scenic Luxury Cruises, Scenic Amber
Scenic Amber Cruises17 Night - Jewels of Europe with Paris
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Nov 2, 2027: May 10, More...
Viking River, Viking Gefjon
Viking Gefjon Cruises14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Nov 3, More...
Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II Cruises15 Night - Enchanted Europe for Beer Enthusiasts (Westbound)
Starting in Budapest (Embarkation), Hungary, Vienna, Austria, Vienna, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Nuremberg-excursion to Munich, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Seligenstadt, Boppard, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Nov 4, More...
Avalon Waterways, Avalon Expression
Avalon Expression Cruises8 Night - German Grandeur for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg (Disembarkation)
2026 Sails: Nov 6, More...
Avalon Waterways Cruise Tours, Avalon Expression Cruise Tours
Avalon Expression Cruises10 Night - German Grandeur with in Munich for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg (Disembarkation) Munich, Munich
2026 Sails: Nov 6, More...
Avalon Waterways Cruise Tours, Avalon Tranquility II Cruise Tours
Avalon Tranquility II Cruises10 Night - German Grandeur with in Munich for Beer Enthusiasts (Westbound)
Starting in Munich, Germany, Munich, Munich / Nuremberg (Embarkation), Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Seligenstadt, Boppard, Strasbourg, France, Breisach, Germany (Black Forest), Basel, Switzerland (Disembarkation)
2026 Sails: Nov 9, More...
Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper Cruises14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Nov 10, 2027: Nov 9, More...

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Main River Cruises