Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Plitvice Lakes : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

Avalon Waterways Tours, Avalon Illumination Tours

11 Night - Christmastime from Nuremberg to Basel with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 11, More...

Avalon Waterways Tours, Avalon Illumination Tours

7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Prague, Czech Republic, Prague, Prague / Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 11, More...

Avalon Waterways, Avalon Illumination

9 Night - Christmastime from Nuremberg to Basel
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt Excursion to Rudesheim, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 13, More...

Avalon Waterways, Avalon Illumination

5 Night - Christmastime in the Heart of Germany
Starting in Nuremberg, Germany (Embarkation), Nuremberg, Bamberg, Wurzburg, Miltenberg, Frankfurt (Disembarkation)
2026 Sails: Dec 13, More...

Avalon Waterways, Avalon Imagery II

5 Night - Christmastime in the Heart of Germany
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation)
2026 Sails: Dec 14, More...

Avalon Waterways Tours, Avalon Imagery II Tours

7 Night - Christmastime in the Heart of Germany with in Prague
Starting in Frankfurt, Germany (Embarkation), Main River Village, Wurzburg, Bamberg, Nuremberg, Nuremberg (Disembarkation) Prague, Czech Republic, Prague
2026 Sails: Dec 14, More...

Uniworld, S.S. Emilie

7 Night - Classic Christmas Markets
Starting in Frankfurt, Cruising the Main River, Wertheim, Wurzburg, Kitzingen (Rothenburg), Schweinfurt, Bamberg, Nuremberg
2026 Sails: Dec 15, More...

Avalon Waterways, Avalon Tranquility II

4 Night - Christmastime in Alsace & Germany (Southbound)
Starting in Frankfurt, Germany (Embarkation), Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Dec 16, More...

Uniworld, S.S. Elisabeth

7 Night - Classic Christmas Markets
Starting in Nuremberg, Bamberg, Kitzingen (Rothenburg), Wurzburg, Wurzburg, Wertheim, Frankfurt
2026 Sails: Dec 16, More...

Viking River Tours, Viking Idi Tours

11 Night - Christmas on the Main & Moselle
Starting in Paris, Trier, Bernkastel, Cochem, Mainz, Middle Rhine Scenic Sailing, Heidelberg, Scenic Sailing : Main River, Spessart, Wurzburg, Bamberg, Prague
2026 Sails: Dec 16, 2027: Dec 1, Dec 15, 2028: Nov 29, Dec 13, More...

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