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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Italy Coast : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Avalon Waterways, Avalon Tranquility II
Avalon Tranquility II9 Night - Reflections On the Rhine (Southbound)
Starting in Amsterdam, the Netherlands (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2027 Sails: Jun 5, Jul 8, Aug 30, More...
Avalon Waterways Tours, Avalon Tranquility II Tours
Avalon Tranquility II Tours11 Night - Reflections On the Rhine with in Lucerne (Southbound)
Starting in Amsterdam, the Netherlands (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation) Swiss Alps, Lucerne
2027 Sails: Jun 5, Jul 8, Aug 30, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Linz, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2027 Sails: Jun 5, Oct 9, More...
Riviera Travel, MS Oscar Wilde
MS Oscar Wilde10 Night - Rhine Cruise to Switzerland with Glacier Express Extension
Starting in Cologne, Germany, Rhine River, Koblenz, Germany, Rudesheim, Germany, Speyer, Germany, Rhine River, Basel, Switzerland, Chur, Switzerland, Zermatt, Switzerland
2027 Sails: Jun 5, Jun 29, Jul 20, Aug 10, Aug 14, Aug 31, Sep 25, More...
Viking River, Viking Atla
Viking Atla17 Night - Rhine, Main & Danube Odyssey
Starting in Budapest, Scenic Sailing Danube Bend, Vienna, Krems, Scenic Sailing Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Marktheidenfeld, Scenic Sailing Main River, Frankfurt, Baden-Baden, Strasbourg, Breisach, Basel
2027 Sails: Jun 6, Aug 15, Oct 24, More...
Viking River Tours, Viking Idi Tours
Viking Idi Tours11 Night - Cities of Light
Starting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2027 Sails: Jun 9, 2028: May 24, More...
Avalon Waterways, Avalon Impression
Avalon Impression14 Night - Magnificent Europe
Starting in Amsterdam, the Netherlands (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2027 Sails: Jun 11, Aug 4, Sep 27, 2028: May 9, Jul 4, More...
Viking River, Viking Alsvin
Viking Alsvin7 Night - Castles, Vineyards & Villages
Starting in Amsterdam, Kinderdijk, Cologne, Koblenz, Middle Rhine Scenic Sailing, Scenic Sailing Main River, Wertheim, Wurzburg, Bamberg, Nuremberg
2027 Sails: Jun 11, More...
Amadeus River, Amadeus Cara
Amadeus Cara8 Night - German Riverscapes from Passau to Trier
Starting in Passau, Regensburg, Nuremberg, Bamberg, Ochsenfurt, Wertheim, Koblenz, Trier
2027 Sails: Jun 14, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Jun 15, Aug 8, 2028: May 14, Jul 9, Sep 3, More...

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Main River Cruises