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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Astra
Emerald Astra Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel
2026 Sails: Sep 15, More...
Riviera River Cruises, MS Geoffrey Chaucer
MS Geoffrey Chaucer Cruises14 Night - Cruise the Heart of Europe
Starting in Budapest, Hungary, Bratislava, Slovakia, Vienna, Austria, Melk, Austria, Passau, Germany, Main-Danube Canal, Nuremberg, Germany, Main River, Wurzburg, Miltenberg, Germany, Rudesheim, Germany, Boppard, Germany, Koblenz, Germany, Cologne, Germany
2026 Sails: Sep 16, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises17 Night - Splendours of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Sep 19, More...
Uniworld Boutique River Cruise Collection, S.S. Beatrice
S.S. Beatrice Cruise Ship14 Night - European Jewels
Starting in Amsterdam, Cologne, Rudesheim, Frankfurt (Heidelberg), Wertheim, Wurzburg, Cruising the Main River, Kitzingen (Rothenburg), Bamberg, Nuremberg, Cruising the Main-Danube Canal, Regensburg, Passau, Weissenkirchen (Melk), Tulln, Vienna, Budapest
2026 Sails: Sep 20, More...
Emerald Cruises, Emerald Star
Emerald Star Cruises24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Sep 23, More...
Viking River Cruise Tours, Viking Vidar Cruise Tours
Viking Vidar Cruises22 Night - European Sojourn
Starting in Bucharest, Ruse, Vidin, Scenic Sailing : the Iron Gates, Golubac, Belgrade, Osijek, Kalocsa, Budapest, Vienna, Scenic Sailing : Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing : Main River, Spessart, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing : Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: Sep 29, 2027: May 25, Jul 6, Aug 17, Sep 28, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises28 Night - Romantic Rhine & Moselle with Wonders of Switzerland & Austria
Starting in Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Interlaken, Interlaken, Interlaken / Lucerne and Engelberg / Zurich, Zurich, Zurich / Basel, Breisach, Strasbourg, Mannheim, Rudesheim, Cochem, Bernkastel, Cruising Day, Koblenz, Dusseldorf, Arnhem, Antwerp, Bruinisse, Dordrecht, Amsterdam
2026 Sails: Sep 30, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises17 Night - Jewels of Europe with Paris
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Oct 4, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises20 Night - Jewels of Europe with Paris & Prague
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Oct 4, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Oct 7, More...

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Main River Cruises