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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Sun
Emerald Sun Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Jul 11, 2027: Aug 16, Sep 6, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel
2026 Sails: Jul 11, 2027: Aug 16, Sep 6, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises10 Night - The Majestic Rhine & Lucerne - Zurich
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Lucerne, Lucerne, Lucerne / Zurich, Zurich
2026 Sails: Jul 11, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises17 Night - Jewels of Europe with Paris
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jul 12, Sep 6, Oct 4, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises20 Night - Jewels of Europe with Paris & Prague
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Jul 12, Sep 6, Oct 4, More...
Riviera River Cruises, MS William Wordsworth
MS William Wordsworth Cruises14 Night - Cruise the Heart of Europe
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2026 Sails: Jul 13, More...
Amadeus River Cruises, MS Amadeus Aurea
MS Amadeus Aurea Cruises14 Night - Across Europe - Budapest to Amsterdam
Starting in Budapest, Bratislava, Vienna, Durnstein, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Cologne, Utrecht, Amsterdam
2026 Sails: Jul 14, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Jul 15, Sep 9, Oct 7, 2027: Jul 16, Sep 10, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises28 Night - Jewels of Europe with Wonders of Switzerland & Austria
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Vienna, Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Grindelwald, Grindelwald, Grindelwald / Lucerne and Engelberg / Zurich, Zurich
2026 Sails: Jul 15, More...
Riviera River Cruises, MS George Eliot
MS George Eliot Cruises10 Night - Cologne, the Rhine Gorge & Medieval Germany
Starting in Nuremberg, Germany, Main River, Wurzburg, Germany, Rhine River, Miltenberg, Germany, Mainz, Germany, Boppard, Germany, Andernach, Germany, Cologne, Germany
2026 Sails: Jul 16, Sep 30, More...

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Main River Cruises