Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises14 Night - Splendours of Europe
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jul 3, Sep 28, 2027: Oct 20, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Jul 3, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises10 Night - Berlin & the Majestic Rhine
Starting in Berlin, Berlin / Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel
2026 Sails: Jul 8, 2027: Aug 13, Sep 3, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises13 Night - Berlin to Zurich & the Majestic Rhine
Starting in Berlin, Berlin / Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Lucerne, Lucerne, Lucerne / Zurich, Zurich
2026 Sails: Jul 8, More...
Emerald Cruises, Emerald Sun
Emerald Sun Cruises10 Night - Berlin & the Majestic Rhine
Starting in Berlin, Berlin / Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Jul 8, More...
Avalon Waterways, Avalon Expression
Avalon Expression Cruises21 Night - Iconic Rivers of Europe - the Rhine, Main & Danube
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation)
2026 Sails: Jul 9, More...
Avalon Waterways Cruise Tours, Avalon Expression Cruise Tours
Avalon Expression Cruises24 Night - Iconic Rivers of Europe - the Rhine, Main & Danube with in Bucharest and in Transylvania
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation) Bucharest, Brasov, Brasov / Sinaia / Bucharest, Bucharest
2026 Sails: Jul 9, More...
Avalon Waterways Cruise Tours, Avalon Expression Cruise Tours
Avalon Expression Cruises22 Night - Iconic Rivers of Europe - the Rhine, Main & Danube with in Bucharest
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest, Vukovar, Novi Sad, Serbia, Belgrade, Golubac / Donji Milanovac Excursion to Lepenski Vir / Iron Gates Gorge, Vidin, Bulgaria, Rousse / Veliko Tarnovo and Arbanassi Excursion, Oltenita, Romania (Disembarkation) Bucharest, Bucharest
2026 Sails: Jul 9, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises33 Night - Jewels of Europe with Majestic Britain & Ireland
Starting in Dublin, Dublin / Killarney, Killarney, Killarney / Galway, Galway / Belfast, Belfast, Belfast / Loch Lomond, Loch Lomond, Loch Lomond / Inverness, Inverness, Inverness / Edinburgh, Edinburgh, Edinburgh / York, York, York / Bath, Bath, Bath / London, London, London / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jul 10, Sep 4, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises10 Night - Jewels of the Rhine & Glacier Express
Starting in Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim (Heidelberg), Kehl / Strasbourg, Breisach / Freiburg, Basel / Zermatt, Zermatt, Zermatt / Zurich, Zurich
2026 Sails: Jul 11, More...

<= Back
More =>

Main River Cruises