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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Italy Coast : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury, Scenic Amber
Scenic Amber17 Night - Jewels of Europe with Paris
Starting in Budapest, Vienna, Krems / Durnstein, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Amsterdam / Paris, Paris
2027 Sails: May 10, More...
Avalon Waterways, Avalon Imagery II
Avalon Imagery II15 Night - Enchanted Europe for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg-excursion to Munich, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2027 Sails: May 11, Oct 30, 2028: Aug 22, More...
Avalon Waterways Tours, Avalon Imagery II Tours
Avalon Imagery II Tours10 Night - German Grandeur with in Munich for Beer Enthusiasts (Eastbound)
Starting in Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Strasbourg, France, Rudesheim, Germany / Rhine Gorge, Frankfurt Excursion to Seligenstadt, Wertheim, Wurzburg, Bamberg, Nuremberg (Disembarkation) Munich, Munich
2027 Sails: May 11, Oct 30, 2028: Aug 22, More...
Avalon Waterways Tours, Avalon Vista Tours
Avalon Vista Tours17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany / Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, 2028: Apr 26, May 10, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, More...
Riviera Travel, MS Riviera Resplendence
MS Riviera Resplendence14 Night - Cruise the Heart of Europe : Journey Along the Rhine, Main and Danube
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2027 Sails: May 12, Jun 2, Sep 1, Sep 30, More...
Scenic Luxury, Scenic Jade
Scenic Jade23 Night - Jewels of Europe with Eastern Europe Explorer
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2027 Sails: May 12, More...
AmaWaterways Tours, AmaLea Tours
AmaLea Tours18 Night - Magnificent Europe with Amsterdam Pre-Cruise and Budapest Post-Cruise
Starting in Amsterdam, Dusseldorf, Cologne, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2027 Sails: May 13, Jun 10, More...
AmaWaterways Tours, AmaSofia Tours
AmaSofia Tours16 Night - Magnificent Europe with Budapest Pre-Cruise
Starting in Budapest, Bratislava, Vienna, Durnstein, Melk, Linz, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cologne, Amsterdam
2027 Sails: May 13, Jun 10, More...
Emerald Cruises, Emerald Luna
Emerald Luna12 Night - Amsterdam with Jewels of the Rhine & Glacier Express
Starting in Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim / Germersheim, Strasbourg, Breisach, Basel (Huningue) Zermatt, Zermatt, Zermatt / Zurich, Zurich
2027 Sails: May 13, More...
Viking River, Viking Modi
Viking Modi10 Night - Rhine & Main Explorer
Starting in Basel, Breisach, Strasbourg, Baden-Baden, Frankfurt, Scenic Sailing Main River, Marktheidenfeld, Wurzburg, Bamberg, Nuremberg
2027 Sails: May 14, More...

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Main River Cruises