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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Douro River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Manzanares River : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises23 Night - Jewels of Europe with Eastern Europe Explorer
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jul 20, More...
Amadeus River Cruises, MS Amadeus Aurea
MS Amadeus Aurea Cruises7 Night - Three-Rivers Cruise
Starting in Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Cologne, Utrecht, Amsterdam
2026 Sails: Jul 21, More...
AmaWaterways Cruise Tours, AmaPrima Cruise Tours
AmaPrima Cruise Tours13 Night - Europe's Rivers & Castles with Paris Pre-Cruise and Prague Post-Cruise
Starting in Paris, Luxembourg, Bernkastel, Cochem, Koblenz, Rhine Gorge, Rudesheim, Wertheim, Wurzburg, Nuremberg, Prague
2026 Sails: Jul 26, More...
AmaWaterways, AmaPrima
AmaPrima Cruises7 Night - Europe's Rivers & Castles
Starting in Luxembourg, Bernkastel, Cochem, Koblenz, Rhine Gorge, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg
2026 Sails: Jul 29, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises13 Night - London, Jewels of the Rhine & Swiss Glaciers
Starting in London, London / Amsterdam, Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim (Heidelberg), Kehl / Strasbourg, Breisach / Freiburg, Basel / Zermatt, Zermatt, Zermatt / Zurich, Zurich
2026 Sails: Jul 29, More...
Scenic Luxury Cruises, Scenic Pearl
Scenic Pearl Cruises28 Night - Romantic Rhine & Moselle with Wonders of Switzerland & Austria
Starting in Amsterdam, Dordrecht, Bruinisse, Antwerp, Arnhem, Dusseldorf, Cochem, Bernkastel, Koblenz, Rudesheim, Mannheim, Strasbourg, Breisach, Basel / Zurich, Zurich, Zurich / Lucerne and Engelberg / Grindelwald, Grindelwald, Grindelwald / Montreux, Montreux, Montreux / Zermatt, Zermatt, Zermatt / Schwangau, Schwangau, Schwangau / Salzburg, Salzburg, Salzburg / Vienna, Vienna
2026 Sails: Jul 29, More...
Scenic Luxury Cruises, Scenic Ruby
Scenic Ruby Cruises28 Night - Romantic Rhine & Moselle with Wonders of Switzerland & Austria
Starting in Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Grindelwald, Grindelwald, Grindelwald / Lucerne and Engelberg / Zurich, Zurich, Zurich / Basel, Breisach, Strasbourg, Mannheim, Rudesheim, Cochem, Bernkastel, Cruising Day, Koblenz, Dusseldorf, Arnhem, Antwerp, Bruinisse, Dordrecht, Amsterdam
2026 Sails: Jul 29, More...
Viking River, Viking Lif
Viking Lif Cruises21 Night - Grand European & Viking Fjords
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam, Sail the North Sea, Skagen, Oslo, Kristiansand, Stavanger, Flam, Norway, Bergen
2026 Sails: Jul 29, More...
Riviera River Cruises, MS Emily Bronte
MS Emily Bronte Cruises10 Night - Rhine Cruise to Switzerland (Including Glacier Express Extension)
Starting in Cologne, Germany, Rhine River, Koblenz, Germany, Rudesheim, Germany, Speyer, Germany, Rhine River, Basel, Switzerland, Davos, Switzerland, Zermatt, Switzerland
2026 Sails: Aug 2, 2027: May 3, May 17, Jul 19, Aug 9, Aug 30, Sep 20, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises20 Night - Belgian Delights & Splendours of Europe & Prague
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Aug 5, More...

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Main River Cruises