Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Aug 24, 2027: Apr 26, May 24, Sep 13, More...

Scenic Luxury Cruises, Scenic Amber

17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Aug 24, 2027: Apr 26, May 24, Sep 13, More...

Emerald Cruises, Emerald Astra

10 Night - The Majestic Rhine & Berlin
Starting in Zurich / Basel, Breisach / Colmar, Kehl / Strasbourg, Rastatt (Baden-Baden), Mannheim / Ludwigshafen (Heidelberg), Koblenz, Rudesheim, Mainz / Frankfurt / Berlin, Berlin
2026 Sails: Aug 25, More...

Emerald Cruises, Emerald Astra

10 Night - The Majestic Rhine & Berlin
Starting in Basel, Breisach / Colmar, Kehl / Strasbourg, Rastatt (Baden-Baden), Mannheim / Ludwigshafen (Heidelberg), Koblenz, Rudesheim, Mainz / Frankfurt / Berlin, Berlin
2026 Sails: Aug 25, More...

Scenic Luxury Cruises, Scenic Jade

18 Night - Jewels of Europe with Ljubljana & Zagreb
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Ljubljana, Ljubljana, Ljubljana / Zagreb, Zagreb / Plitvice National Park / Zagreb, Zagreb
2026 Sails: Aug 26, 2027: May 7, Jul 30, More...

Scenic Luxury Cruises, Scenic Jasper

33 Night - Jewels of Europe with Majestic Britain & Ireland
Starting in Dublin, Dublin / Killarney, Killarney, Killarney / Galway, Galway / Belfast, Belfast, Belfast / Loch Lomond, Loch Lomond, Loch Lomond / Inverness, Inverness, Inverness / Edinburgh, Edinburgh, Edinburgh / York, York, York / Bath, Bath, Bath / London, London, London / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Aug 27, More...

Uniworld Boutique River Cruise Tours, S.S. Beatrice Cruise Tours

23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: Aug 28, More...

Scenic Luxury Cruises, Scenic Jasper

17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Aug 29, 2027: Jul 10, Aug 7, Oct 2, More...

AmaWaterways Cruise Tours, AmaCerto Cruise Tours

13 Night - Europe's Rivers & Castles with Prague Pre-Cruise and Paris Post-Cruise
Starting in Prague, Nuremberg, Bamberg, Wurzburg, Wertheim, Rudesheim, Rhine Gorge, Lahnstein, Cochem, Wasserbillig, Luxembourg, Paris
2026 Sails: Aug 30, Oct 25, 2027: Mar 28, May 9, Jul 18, Aug 29, Oct 10, More...

Emerald Cruises, Emerald Destiny

7 Night - The Majestic Rhine
Starting in Frankfurt / Mainz, Rudesheim, Koblenz, Mannheim / Ludwigshafen / Heidelberg, Rastatt (Baden-Baden), Kehl / Strasbourg, Breisach / Colmar, Basel / Zurich
2026 Sails: Aug 31, 2027: Jul 11, More...

<= Back

More =>