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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 23, Aug 4, Sep 29, 2027: Jun 1, Jul 13, Aug 10, Sep 7, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Jun 23, 2027: Aug 10, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises17 Night - Paris & Splendours of Europe
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jun 24, Sep 16, 2027: Jun 23, Aug 4, More...
Emerald Cruises, Emerald Luna
Emerald Luna Cruises20 Night - Paris to Prague & Splendours of Europe
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Jun 24, Sep 16, 2027: Jun 23, Aug 4, More...
Viking River Cruise Tours, Viking Idi Cruise Tours
Viking Idi Cruises11 Night - Cities of Light
Starting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Jun 24, More...
Avalon Waterways, Avalon Expression
Avalon Expression Cruises14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 25, Aug 20, Oct 16, 2027: May 10, Jul 3, Aug 26, Oct 19, More...
Riviera River Cruises, MS George Eliot
MS George Eliot Cruises7 Night - Medieval Germany : Bavaria & the Romantic Road
Starting in Mainz, Germany, Miltenberg, Germany, Main River, Wurzburg, Germany, Main River, Mainz, Germany
2026 Sails: Jun 25, Jul 9, Aug 26, Sep 9, Sep 23, More...
Riviera River Cruises, MS Oscar Wilde
MS Oscar Wilde Cruises10 Night - Rhine Cruise to Switzerland (Including Glacier Express Extension)
Starting in Cologne, Germany, Rhine River, Koblenz, Germany, Rudesheim, Germany, Speyer, Germany, Rhine River, Basel, Switzerland, Davos, Switzerland, Zermatt, Switzerland
2026 Sails: Jun 26, 2027: Jun 1, Jun 29, Sep 21, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jun 27, Sep 19, 2027: Apr 24, Sep 25, Oct 23, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises17 Night - Splendours of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 27, Sep 19, More...

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Main River Cruises