Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Italy Coast : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

14 Night - Magnificent Europe
Starting in Budapest, Bratislava, Vienna, Durnstein, Melk, Linz, Engelhartszell, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Freudenberg, Rudesheim, Lahnstein, Cologne, Amsterdam
2027 Sails: May 1, May 29, 2028: Apr 29, May 27, More...

AmaWaterways, AmaSofia

14 Night - Magnificent Europe
Starting in Amsterdam, Dusseldorf, Cologne, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2027 Sails: May 1, May 29, 2028: Feb 19, Apr 29, May 27, More...

AmaWaterways Tours, AmaCerto Tours

14 Night - Medieval Treasures with Zurich, Lake Lucerne Pre-Cruise and Prague Post-Cruise
Starting in Zurich, Basel, Strasbourg, Ludwigshafen, Frankfurt, Miltenberg, Wertheim, Wurzburg, Eltmann, Nuremberg, Prague
2027 Sails: May 1, Jul 10, Aug 21, Oct 2, More...

Emerald Cruises, Emerald Luna

10 Night - Jewels of the Rhine & Glacier Express
Starting in Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim / Germersheim, Strasbourg, Breisach, Basel (Huningue) Zermatt, Zermatt, Zermatt / Zurich, Zurich
2027 Sails: May 1, May 15, Jun 12, More...

Emerald Cruises, Emerald Star

14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2027 Sails: May 1, Jun 26, Aug 7, Sep 4, Oct 2, Oct 30, 2028: Jun 3, Oct 20, More...

Uniworld Tours, S.S. Audrey Tours

11 Night - Paris, Prague & Germany's Hidden Gems
Starting in Paris, Paris, Trier, Trier, Luxembourg, Cochem, Rudesheim, Aschaffenburg (Heidelberg), Wertheim, Kitzingen, Volkach, Bamberg, Prague, Prague, Depart Prague
2027 Sails: May 1, Jun 18, Jul 16, More...

Avalon Waterways, Avalon Imagery II

9 Night - Reflections On the Rhine (Southbound)
Starting in Amsterdam, the Netherlands (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2027 Sails: May 2, 2028: May 14, Jun 16, Jul 25, Aug 13, More...

Avalon Waterways Tours, Avalon Imagery II Tours

11 Night - Reflections On the Rhine with in Lucerne (Southbound)
Starting in Amsterdam, the Netherlands (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Ludwigshafen Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation) Swiss Alps, Lucerne
2027 Sails: May 2, 2028: May 14, Jun 16, Jul 25, Aug 13, More...

Riviera Travel, MS Riviera Radiance

14 Night - Cruise the Heart of Europe : Journey Along the Rhine, Main and Danube
Starting in Cologne, Germany, Koblenz, Germany, Boppard, Germany, Rudesheim, Germany, Miltenberg, Germany, Wurzburg, Main River, Nuremberg, Germany, Main-Danube Canal, Passau, Germany, Melk, Austria, Vienna, Austria, Bratislava, Slovakia, Budapest, Hungary
2027 Sails: May 2, May 16, More...

Scenic Luxury, Scenic Jewel

33 Night - Jewels of Europe with Majestic Britain & Ireland
Starting in Dublin, Dublin / Killarney, Killarney, Killarney / Galway, Galway / Belfast, Belfast, Belfast / Loch Lomond, Loch Lomond, Loch Lomond / Inverness, Inverness, Inverness / Edinburgh, Edinburgh, Edinburgh / York, York, York / Bath, Bath, Bath / London, London, London / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Durnstein / Krems, Vienna, Budapest
2027 Sails: May 2, Jun 27, More...

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