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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Viking River Cruise Tours, Viking Vidar Cruise Tours
Viking Vidar Cruises22 Night - European Sojourn
Starting in Amsterdam, Kinderdijk, Scenic Sailing : Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing : Main River, Spessart, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing : Wachau Valley, Krems, Vienna, Budapest, Kalocsa, Osijek, Belgrade, Golubac, Scenic Sailing : the Iron Gates, Vidin, Ruse, Bucharest
2026 Sails: Jun 17, Jul 29, Sep 9, Oct 21, 2027: Jun 16, Jul 28, Sep 8, Oct 20, More...
Riviera River Cruises, MS George Eliot
MS George Eliot Cruises7 Night - Medieval Germany : Bavaria & the Romantic Road
Starting in Mainz, Germany, Main River, Wurzburg, Germany, Main River, Miltenberg, Germany, Mainz, Germany
2026 Sails: Jun 18, Jul 2, Sep 2, Sep 16, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises22 Night - Discover the Rhine, Main & Danube Rivers
Starting in Bucharest, Bucharest / Giurgiu, Rousse, Vidin, Donji Milanovac / Golubac, Belgrade, Vukovar, Kalocsa, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jun 19, Sep 11, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises14 Night - Splendours of Europe
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jun 19, Oct 12, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Splendours of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 19, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises14 Night - Splendours of Europe
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jun 19, Jul 17, Oct 11, 2027: Mar 8, Jun 20, Sep 22, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Jun 19, Jul 17, Oct 11, 2027: Sep 22, More...
Viking River, Viking Idi
Viking Idi Cruises7 Night - Castles, Vineyards & Villages
Starting in Amsterdam, Kinderdijk, Cologne, Koblenz, Middle Rhine Scenic Sailing, Scenic Sailing Main River, Wertheim, Wurzburg, Bamberg, Nuremberg
2026 Sails: Jun 19, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruises14 Night - Swiss Splendors by Train with Romantic Rhine Cruise
Starting in Arrive in Lake Geneva, Switzerland, Lake Geneva, Lake Geneva / Zermatt / Gornergrat Excursion, Zermatt / Interlaken, Interlaken, Interlaken / Brienz / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 20, More...
Emerald Cruises, Emerald Astra
Emerald Astra Cruises10 Night - Jewels of the Rhine & Glacier Express
Starting in Amsterdam, Dusseldorf / Cologne, Koblenz, Mannheim (Heidelberg), Kehl / Strasbourg, Breisach / Freiburg, Basel / Zermatt, Zermatt, Zermatt / Zurich, Zurich
2026 Sails: Jun 20, Jul 4, Aug 1, More...

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Main River Cruises