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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Splendours of Europe & Paris
Starting in Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 19, More...
Viking River, Viking Idi
Viking Idi Cruises7 Night - Castles, Vineyards & Villages
Starting in Amsterdam, Kinderdijk, Cologne, Koblenz, Middle Rhine Scenic Sailing, Scenic Sailing Main River, Wertheim, Wurzburg, Bamberg, Nuremberg, Bamberg
2026 Sails: Jun 19, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruises14 Night - Swiss Splendors by Train with Romantic Rhine Cruise
Starting in Arrive in Lake Geneva, Switzerland, Lake Geneva, Lake Geneva / Zermatt / Gornergrat Excursion, Zermatt / Interlaken, Interlaken, Interlaken / Brienz / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 20, Jul 4, More...
Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper Cruises17 Night - Jewels of Europe with Prague
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 20, More...
Scenic Luxury Cruises, Scenic Jasper
Scenic Jasper Cruises20 Night - Jewels of Europe with Prague & Paris
Starting in Prague, Prague / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 20, More...
Scenic Luxury Cruises, Scenic Opal
Scenic Opal Cruises17 Night - Jewels of Europe with Paris
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 20, More...
Uniworld Boutique River Cruise Collection, River Duchess
River Duchess Cruise Ship14 Night - European Jewels
Starting in Amsterdam, Cologne, Rudesheim, Frankfurt (Heidelberg), Wertheim, Wurzburg, Cruising the Main River, Kitzingen (Rothenburg), Bamberg, Nuremberg, Cruising the Main-Danube Canal, Regensburg, Passau, Weissenkirchen (Melk), Tulln, Vienna, Budapest
2026 Sails: Jun 21, Sep 13, Oct 11, More...
Uniworld Boutique River Cruise Tours, River Duchess Cruise Tours
River Duchess Cruise Ship23 Night - Ultimate European Journey
Starting in Amsterdam, Cologne, Rudesheim, Frankfurt (Heidelberg), Wertheim, Wurzburg, Cruising the Main River, Kitzingen (Rothenburg), Bamberg, Nuremberg, Cruising the Main-Danube Canal, Regensburg, Passau, Weissenkirchen (Melk), Tulln, Vienna, Budapest, Batina (Osijek), Vukovar, Belgrade, Golubac, Cruising the Iron Gates, Vidin, Ruse, Giurgiu, Transfer to Bucharest, Bucharest
2026 Sails: Jun 21, More...
Amadeus River Cruises, MS Amadeus Aurea
MS Amadeus Aurea Cruises7 Night - Rhine & Danube Symphony
Starting in Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau
2026 Sails: Jun 23, More...
Avalon Waterways, Avalon Impression
Avalon Impression Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Jun 23, Aug 18, Oct 13, 2027: Jun 11, Aug 4, Sep 27, More...

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Main River Cruises