Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

7 Night - Castles, Vineyards & Villages
Starting in Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Kinderdijk, Amsterdam
2026 Sails: Jun 5, More...

Scenic Luxury Cruises, Scenic Jasper

17 Night - Jewels of Europe with Paris
Starting in Paris, Paris / Amsterdam, Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 6, Aug 15, More...

Uniworld Boutique River Cruise Collection, River Duchess

14 Night - European Jewels
Starting in Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: Jun 7, Jul 19, Aug 30, Sep 27, Oct 25, More...

Riviera River Cruises, MS George Eliot

10 Night - Cologne, the Rhine Gorge & Medieval Germany
Starting in Cologne, Germany, Andernach, Germany, Boppard, Germany, Mainz, Germany, Miltenberg, Germany, Rhine River, Wurzburg, Germany, Main River, Nuremberg, Germany
2026 Sails: Jun 8, Aug 9, More...

Scenic Luxury Cruises, Scenic Jade

23 Night - Jewels of Europe with Eastern Europe Explorer
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow, Krakow / Budapest, Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 8, More...

Scenic Luxury Cruises, Scenic Jasper

14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 9, Jul 7, Aug 18, Sep 15, 2027: Jun 15, Jul 27, Aug 24, Sep 21, More...

Scenic Luxury Cruises, Scenic Jasper

17 Night - Jewels of Europe with Prague
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Prague, Prague
2026 Sails: Jun 9, Aug 18, 2027: Jun 15, Jul 27, More...

Scenic Luxury Cruises, Scenic Opal

14 Night - Jewels of Europe
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jun 9, Jul 7, Aug 18, Sep 15, Oct 27, 2027: Mar 23, Jun 15, Jul 27, Aug 24, More...

Viking River, Viking Alsvin

7 Night - Castles, Vineyards & Villages
Starting in Amsterdam, Kinderdijk, Cologne, Koblenz, Middle Rhine Scenic Sailing, Scenic Sailing Main River, Wertheim, Wurzburg, Bamberg, Nuremberg
2026 Sails: Jun 12, More...

Viking River, Viking Idi

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