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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Viking River, Viking Gullveig
Viking Gullveig Cruises17 Night - Rhine, Main & Danube Odyssey
Starting in Budapest, Scenic Sailing Danube Bend, Vienna, Krems, Scenic Sailing Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Marktheidenfeld, Scenic Sailing Main River, Frankfurt, Karlsruhe, Strasbourg, Breisach, Basel
2026 Sails: Jun 13, Aug 22, Oct 31, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises20 Night - Prague to Paris & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: Jun 16, More...
Emerald Cruises, Emerald Destiny
Emerald Destiny Cruises17 Night - Prague & Splendours of Europe
Starting in Prague, Prague / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jun 16, Oct 9, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises20 Night - Belgian Delights & Splendours of Europe & Prague
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: Jun 16, More...
Emerald Cruises, Emerald Sky
Emerald Sky Cruises17 Night - Belgian Delights & Splendours of Europe
Starting in Brussels, Brussels / Amsterdam, Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest
2026 Sails: Jun 16, 2027: Jun 17, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: Jun 17, Aug 12, Sep 9, More...
Scenic Luxury Cruises, Scenic Jewel
Scenic Jewel Cruises14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 17, Aug 12, Sep 9, Oct 7, 2027: Apr 23, May 21, Jun 18, Jul 16, Aug 13, Sep 10, Oct 8, More...
Scenic Luxury Cruises, Scenic Pearl
Scenic Pearl Cruises28 Night - Romantic Rhine & Moselle with Wonders of Switzerland & Austria
Starting in Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Interlaken, Interlaken, Interlaken / Lucerne and Engelberg / Zurich, Zurich, Zurich / Basel, Breisach, Strasbourg, Mannheim, Rudesheim, Cochem, Bernkastel, Cruising Day, Koblenz, Dusseldorf, Arnhem, Antwerp, Bruinisse, Dordrecht, Amsterdam
2026 Sails: Jun 17, More...
Viking River Cruise Tours, Viking Alsvin Cruise Tours
Viking Alsvin Cruises11 Night - Cities of Light
Starting in Prague, Bamberg, Scenic Sailing : Main River, Spessart, Wurzburg, Heidelberg, Mainz, Rudesheim, Middle Rhine Scenic Sailing, Cochem, Bernkastel, Trier, Paris
2026 Sails: Jun 17, More...
Riviera River Cruises, MS George Eliot
MS George Eliot Cruises7 Night - Medieval Germany : Bavaria & the Romantic Road
Starting in Mainz, Germany, Main River, Wurzburg, Germany, Main River, Miltenberg, Germany, Mainz, Germany
2026 Sails: Jun 18, Jul 2, Sep 2, Sep 16, More...

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Main River Cruises