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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Viking River, Viking Lif
Viking Lif Cruises14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: May 20, Jul 1, Aug 12, Sep 23, Nov 4, 2027: May 19, Jun 30, Aug 11, Sep 22, Nov 3, More...
Viking River, Viking Modi
Viking Modi Cruises17 Night - Rhine, Main & Danube Odyssey
Starting in Basel, Breisach, Strasbourg, Karlsruhe, Frankfurt, Scenic Sailing Main River, Marktheidenfeld, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Scenic Sailing Wachau Valley, Krems, Vienna, Scenic Sailing Danube Bend, Budapest
2026 Sails: May 21, Jun 30, Oct 28, More...
AmaWaterways Cruise Tours, AmaSofia Cruise Tours
AmaSofia Cruise Tours18 Night - Magnificent Europe with Amsterdam Pre-Cruise and Budapest Post-Cruise
Starting in Amsterdam, Dusseldorf, Rudesheim, Wertheim, Wurzburg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 22, More...
AmaWaterways, AmaSofia
AmaSofia Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Dusseldorf, Rudesheim, Wertheim, Wurzburg, Eltmann, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 24, More...
Viking River, Viking Atla
Viking Atla Cruises17 Night - Rhine, Main & Danube Odyssey
Starting in Budapest, Scenic Sailing Danube Bend, Vienna, Krems, Scenic Sailing Wachau Valley, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Marktheidenfeld, Scenic Sailing Main River, Frankfurt, Karlsruhe, Strasbourg, Breisach, Basel
2026 Sails: May 24, Aug 2, Oct 11, More...
Viking River Cruise Tours, Viking Vidar Cruise Tours
Viking Vidar Cruises22 Night - European Sojourn
Starting in Bucharest, Ruse, Vidin, Scenic Sailing : the Iron Gates, Golubac, Belgrade, Osijek, Kalocsa, Budapest, Vienna, Scenic Sailing : Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing : Main River, Spessart, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing : Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: May 26, Jul 7, Aug 18, Sep 29, 2027: May 25, Jul 6, Aug 17, Sep 28, More...
Viking River Cruise Tours, Viking Alsvin Cruise Tours
Viking Alsvin Cruises11 Night - Cities of Light
Starting in Paris, Trier, Bernkastel, Cochem, Koblenz, Middle Rhine Scenic Sailing, Heidelberg, Scenic Sailing : Main River, Spessart, Wurzburg, Bamberg, Nuremberg, Prague
2026 Sails: May 27, More...
Amadeus River Cruises, MS Amadeus Cara
MS Amadeus Cara Cruises7 Night - Three-Rivers Cruise
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg, Wurzburg, Bamberg, Nuremberg
2026 Sails: May 28, More...
Uniworld Boutique River Cruise Tours, River Duchess Cruise Tours
River Duchess Cruise Ship23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: May 29, Jul 10, Aug 21, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: May 30, Aug 1, Sep 26, 2027: Jun 29, Aug 22, More...

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Main River Cruises