Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

14 Night - Magnificent Europe
Starting in Budapest, Bratislava, Vienna, Durnstein, Melk, Linz, Engelhartszell, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim, Freudenberg, Rudesheim, Lahnstein, Dusseldorf, Amsterdam
2026 Sails: May 16, Jun 13, More...

Avalon Waterways, Avalon Illumination

14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 16, Jul 11, Sep 12, 2027: Jun 15, Aug 8, More...

Avalon Waterways, Avalon Imagery II

9 Night - Reflections On the Rhine (Southbound)
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: May 17, Jun 5, Jul 8, Aug 10, Oct 2, More...

Avalon Waterways Cruise Tours, Avalon Imagery II Cruise Tours

11 Night - Reflections On the Rhine with in Lucerne (Southbound)
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation) Swiss Alps, Lucerne
2026 Sails: May 17, Jun 5, Jul 8, Aug 10, Oct 2, More...

Riviera River Cruises, MS George Eliot

14 Night - Cruise the Heart of Europe
Starting in Budapest, Hungary, Bratislava, Slovakia, Vienna, Austria, Melk, Austria, Passau, Germany, Main-Danube Canal, Nuremberg, Germany, Main River, Wurzburg, Miltenberg, Germany, Rudesheim, Germany, Boppard, Germany, Koblenz, Germany, Cologne, Germany
2026 Sails: May 18, 2027: Aug 18, More...

Scenic Luxury Cruises, Scenic Crystal

14 Night - Jewels of Europe
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: May 19, 2027: Apr 24, Sep 13, More...

Viking River, Viking Gefjon

14 Night - Grand European Tour
Starting in Budapest, Vienna, Scenic Sailing Wachau Valley, Melk, Passau, Regensburg, Main-Danube Canal, Nuremberg, Bamberg, Wurzburg, Wertheim, Scenic Sailing Main River, Middle Rhine Scenic Sailing, Koblenz, Cologne, Scenic Sailing Waal and Merwede, Kinderdijk, Amsterdam
2026 Sails: May 19, Jun 16, Jul 14, Aug 11, Sep 8, Oct 6, More...

Emerald Cruises, Emerald Sun

24 Night - Eastern European Escapade & Splendours of Europe
Starting in Prague, Prague / Dresden / Berlin, Berlin, Berlin / Warsaw, Warsaw, Warsaw / Krakow, Krakow / Auschwitz, Krakow / Budapest, Budapest, Bratislava, Vienna, Durnstein / Melk, Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Koblenz, Cologne, Amsterdam
2026 Sails: May 20, More...

Scenic Luxury Cruises, Scenic Jade

17 Night - Jewels of Europe with Paris
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam, Amsterdam / Paris, Paris
2026 Sails: May 20, Aug 12, Sep 9, 2027: Mar 12, Apr 23, May 21, Oct 8, More...

Viking River, Viking Eldir

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