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Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail: Aare River : Amstel River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Norway Coast : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River


Uniworld Boutique River Cruise Tours, River Duchess Cruise Tours
River Duchess Cruise Ship23 Night - Ultimate European Journey
Starting in Bucharest, Bucharest, Transfer to Giurgiu, Ruse, Vidin, Cruising the Iron Gates, Donji Milanovac, Golubac, Belgrade, Ilok, Aljmas, Budapest, Cruising the Danube River, Vienna, Vienna, Cruising the Wachau Valley, Weissenkirchen (Melk), Passau, Regensburg, Nuremberg, Bamberg, Wurzburg (Rothenburg), Wertheim, Frankfurt (Heidelberg), Rudesheim, Cologne, Amsterdam
2026 Sails: May 29, Jul 10, Aug 21, More...
AmaWaterways, AmaStella
AmaStella Cruises14 Night - Magnificent Europe (Smithsonian Journeys)
Starting in Amsterdam, Cologne, Rudesheim, Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk, Vienna, Budapest
2026 Sails: May 30, More...
Avalon Waterways, Avalon Illumination
Avalon Illumination Cruises14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: May 30, Aug 1, Sep 26, 2027: Jun 29, Aug 22, More...
Emerald Cruises, Emerald Dawn
Emerald Dawn Cruises17 Night - Splendours of Europe & Prague
Starting in Amsterdam, Cologne, Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau, Melk / Durnstein, Vienna, Bratislava, Budapest, Budapest / Prague, Prague
2026 Sails: May 30, Aug 8, Sep 5, 2027: May 8, Oct 9, More...
Viking River, Viking Magni
Viking Magni Cruises14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: May 31, Jun 28, Jul 26, Aug 23, Sep 20, Oct 18, Nov 15, More...
Avalon Waterways, Avalon Impression
Avalon Impression Cruises14 Night - Magnificent Rivers of Europe
Starting in Budapest, Hungary (Embarkation), Budapest, Bratislava, Slovakia, Vienna, Austria, Durnstein / Wachau Valley, Passau, Germany, Regensburg, Roth Excursion to Nuremberg, Bamberg, Wurzburg, Miltenberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 2, Aug 4, Sep 29, 2027: May 28, Jul 21, Sep 13, More...
Scenic Luxury Cruises, Scenic Crystal
Scenic Crystal Cruises14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jun 2, 2027: May 8, Sep 27, More...
Avalon Waterways Cruise Tours, Avalon Vista Cruise Tours
Avalon Vista Cruises17 Night - The Best of Austria & Switzerland with Romantic Rhine
Starting in Vienna, Austria, Vienna, Vienna / Mondsee / Salzburg, Salzburg, Salzburg / Innsbruck / St Moritz, Switzerland, St Moritz / Chur / Zermatt, Zermatt, Zermatt / Bern, Bern / Interlaken / Lucerne, Lucerne, Lucerne / Basel, Switzerland (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
Scenic Luxury Cruises, Scenic Jade
Scenic Jade Cruises28 Night - Jewels of Europe with Wonders of Switzerland & Austria
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest, Budapest / Vienna, Vienna, Vienna / Salzburg, Salzburg, Schwangau, Schwangau / Zermatt, Zermatt, Montreux, Montreux / Interlaken, Interlaken, Interlaken / Lucerne and Engelberg / Zurich, Zurich
2026 Sails: Jun 3, More...
Viking River, Viking Eldir
Viking Eldir Cruises14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: Jun 3, Jul 15, Aug 26, Oct 7, More...

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Main River Cruises