United States River Cruises

River Cruises that visit North America: United States

River Cruises that depart from United States

See all Cruises that visit United States

Click on a cruise ship itinerary that visits United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Alabama : Alaska : Connecticut : Florida : Georgia : Illinois : Indiana : Iowa : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Mississippi : Missouri : New Hampshire : New York : North Carolina : Ohio : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Vermont : Virginia : Washington : Washington DC : Wisconsin

American Cruise Lines, American Heritage

8 Night - Upper Mississippi River Cruise
Starting in St Louis, MO / Alton, IL, Cruising the Mississippi River, Hannibal, MO, Day of Cruising, Muscatine, IA, Dubuque, IA, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Sep 4, 2027: Sep 10, 2028: Sep 9, More...

American Cruise Lines, American Heritage

15 Night - Grand Heartland Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Dubuque, IA, Davenport, IA, Day of Cruising, Hannibal, MO, Day of River Cruising, St Louis, MO, Memphis, TN, Tunica, MS, Day of Cruising, Vicksburg, MS, Natchez, MS, Baton Rouge, LA, New Orleans, La
2026 Sails: Sep 11, 2027: Sep 17, 2028: Sep 16, More...

American Cruise Lines, American Patriot

8 Night - Maine Coast & Harbors Cruise
Starting in Bangor ME, Day of Cruising the Maine Coast, Bar Harbor, Me, Rockland, ME / Camden, ME, Bath, ME, Boothbay Harbor, ME, Day of Cruising, Portland ME
2026 Sails: Sep 11, Sep 25, More...

American Cruise Lines, American Patriot

8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...

American Cruise Lines, American Ranger

7 Night - Hudson River Fall Foliage Cruises
Starting in New York, NY, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2026 Sails: Sep 19, Oct 3, Oct 17, More...

American Cruise Lines, American Legend

7 Night - Yankee Seaports Cruise
Starting in Boston, Ma, Plymouth, MA, Newport, Ri, New London / Mystic, CT, Sag Harbor, NY, Old Saybrook, CT, New York, NY
2026 Sails: Sep 25, 2027: Jun 6, 2028: Jun 17, Jul 22, More...

American Cruise Lines, American Serenade

15 Night - Grand Heartland Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Dubuque, IA, Davenport, IA, Day of Cruising, Hannibal, MO, Day of River Cruising, St Louis, MO, Memphis, TN, Tunica, MS, Day of Cruising, Vicksburg, MS, Natchez, MS, Baton Rouge, LA, New Orleans, La
2026 Sails: Sep 25, 2027: Sep 24, 2028: Sep 23, More...

American Cruise Lines, American Ranger

7 Night - Hudson River Fall Foliage Cruises
Starting in Albany NY, Catskill, NY, Kingston, NY / Hyde Park, NY, Day of Cruising, West Point, NY, Sleepy Hollow, NY, New York, NY
2026 Sails: Sep 26, Oct 10, Oct 24, More...

American Cruise Lines, American Liberty

American Cruise Lines, American Heritage

11 Night - Mississippi Explorer Cruise
Starting in Memphis, TN, Cruising the Mississippi River, Tunica, MS, Cleveland, MS, Day of River Cruising, Vicksburg, MS, Day of River Cruising, Natchez, MS, St Francisville, LA, Baton Rouge, LA, Oak Alley, LA / Houmas House, LA, New Orleans, La
2026 Sails: Oct 2, More...

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United States River Cruises