South America River Cruises
River Cruises that visit South America
River Cruises by region
See all South America Cruises
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Nov 28, Dec 12, Dec 26, More...
5 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Nov 30, Dec 7, More...
8 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Dec 5, Dec 12, Dec 19, 2027: Jan 9, Jan 16, Jan 23, Mar 13, Mar 20, Mar 27, Apr 10, Apr 17, Apr 24, Jun 12, Jun 19, Jun 26, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Sep 4, Sep 11, Sep 18, Sep 25, More...
7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Dec 9, Dec 23, More...8 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Dec 11, 2027: May 17, Jul 19, Aug 2, Aug 16, Nov 26, Dec 3, Dec 13, 2028: Apr 17, Apr 24, May 1, May 29, Jun 5, Jun 12, Jul 14, Jul 21, Jul 28, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, 2029: Jan 1, Jan 8, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Jan 19, Feb 2, Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, More...10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Jan 19, Feb 2, Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, More...7 Night - Wonders of Colombia
Starting in Cartagena CO, Gambote / Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla
2027 Sails: Jan 13, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Aug 25, Sep 8, Oct 6, Nov 3, Nov 17, Dec 1, Dec 15, 2028: Jan 12, Jan 26, Mar 8, Mar 22, Apr 5, Apr 19, May 3, Sep 6, More...
River Cruises that visit South America
River Cruises by region
See all South America Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Nov 28, Dec 12, Dec 26, More...
5 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Nov 30, Dec 7, More...
8 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Dec 5, Dec 12, Dec 19, 2027: Jan 9, Jan 16, Jan 23, Mar 13, Mar 20, Mar 27, Apr 10, Apr 17, Apr 24, Jun 12, Jun 19, Jun 26, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Sep 4, Sep 11, Sep 18, Sep 25, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Dec 9, Dec 23, More...
8 Night - Upper Amazon : a River ExpeditionStarting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Dec 11, 2027: May 17, Jul 19, Aug 2, Aug 16, Nov 26, Dec 3, Dec 13, 2028: Apr 17, Apr 24, May 1, May 29, Jun 5, Jun 12, Jul 14, Jul 21, Jul 28, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, 2029: Jan 1, Jan 8, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2028: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 12, Mar 26, Apr 9, Apr 23, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Jan 19, Feb 2, Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, More...
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Jan 19, Feb 2, Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, More...
7 Night - Wonders of ColombiaStarting in Cartagena CO, Gambote / Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla
2027 Sails: Jan 13, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Aug 25, Sep 8, Oct 6, Nov 3, Nov 17, Dec 1, Dec 15, 2028: Jan 12, Jan 26, Mar 8, Mar 22, Apr 5, Apr 19, May 3, Sep 6, More...
