South America River Cruises
River Cruises that visit South America
River Cruises by region
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Related areas: Brazil : Colombia : Ecuador : Peru
10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, Dec 9, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: May 30, Jun 27, Jul 11, Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 30, Jun 13, Jun 27, Jul 11, Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, More...9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Jun 4, Jun 18, Jul 2, Jul 16, Aug 27, Sep 10, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, More...7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, More...
River Cruises that visit South America
River Cruises by region
See all South America Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Brazil : Colombia : Ecuador : Peru
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 27, Jun 10, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, Dec 9, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
7 Night - Magic of ColombiaStarting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: May 30, Jun 27, Jul 11, Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...
10 Night - Magic of Colombia with Panama Post CruiseStarting in Barranquilla, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia, Panama City
2026 Sails: May 30, Jun 13, Jun 27, Jul 11, Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, More...
9 Night - Wonders of Colombia with in Cartagena Pre CruiseStarting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Jun 4, Jun 18, Jul 2, Jul 16, Aug 27, Sep 10, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, More...
7 Night - Wonders of ColombiaStarting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
10 Night - Wonders of Colombia with in Panama City Post CruiseStarting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, More...
