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South America River Cruises

River Cruises that visit South America

River Cruises by region

See all South America Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Brazil : Colombia : Ecuador : Peru

South America
Shore Excursions

AmaWaterways, AmaMelodia
AmaMelodia7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 28, Nov 11, Nov 25, More...
Lindblad Expeditions Tours, Delfin III Tours
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Cusco / Sacred Valley, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jul 23, Aug 13, Aug 20, Sep 10, Nov 5, Nov 26, Dec 3, More...
Lindblad Expeditions Tours, Delfin III Tours
Delfin III Tours5 Night - Upper Amazon : a River Expedition
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Nauta / Disembark Ship / Iquitos / Lima
2026 Sails: Jul 27, Aug 17, Aug 24, Sep 14, Nov 9, Nov 30, Dec 7, More...
Lindblad Expeditions Tours, Delfin III Tours
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Iquitos / Lima / Cusco, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima
2026 Sails: Jul 27, Aug 24, Sep 14, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Aug 2, Aug 16, Aug 30, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Aug 2, Aug 16, Aug 30, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City, Barranquilla, Panama City
2026 Sails: Aug 7, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 10, Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...

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South America River Cruises