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South America River Cruises

River Cruises that visit South America

River Cruises by region

See all South America Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Brazil : Colombia : Ecuador : Peru

South America
Shore Excursions

AmaWaterways, AmaMagdalena
AmaMagdalena7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Aug 22, Sep 5, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Aug 24, Sep 7, Oct 5, Oct 19, Nov 16, Nov 30, 2027: May 17, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 24, Sep 7, Oct 5, Oct 19, Nov 16, Nov 30, 2027: May 17, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...
Lindblad Expeditions Tours, Delfin III Tours
Delfin III Tours9 Night - Exploring Peru : Machu Picchu and the Amazon
Starting in Lima, Peru, Lima / Iquitos / Nauta / Embark Ship, Pacaya-Samiria Reserve, Iquitos / Lima / Cusco, Machu Picchu, Sacred Valley / Cusco, Cusco, Cusco / Lima
2026 Sails: Aug 24, Sep 14, More...
AmaWaterways, AmaMelodia
AmaMelodia7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 27, Sep 10, Oct 8, Oct 22, Nov 19, Dec 3, 2027: May 20, More...
AmaWaterways, AmaMagdalena
AmaMagdalena7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 29, Sep 12, Oct 10, Oct 24, Nov 21, Dec 5, Dec 19, 2027: May 22, More...

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South America River Cruises