Siem Reap River Cruise Departures
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
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10 Night - Enchanting Mekong and Siem Reap
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation
2026 Sails: Feb 4, Feb 18, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 13, Apr 10, Apr 24, 2027: Jan 1, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...10 Night - Riches of the Mekong with Siem Reap Pre-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 13, Apr 10, Apr 24, 2027: Jan 1, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...9 Night - Riches of the Mekong with Ho Chi Minh Post-Cruise
Starting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 16, Apr 13, Apr 27, 2027: Jan 4, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, More...
12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2026 Sails: Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 19, Nov 2, Nov 16, Nov 30, More...15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)
Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2026 Sails: Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 19, Nov 2, Nov 16, Nov 30, More...
12 Night - Treasures of the Mekong
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Oct 31, Nov 14, Nov 28, More...10 Night - Luxury Mekong and Temple Discovery Cruise
Starting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, More...14 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Aug 18, Sep 5, Dec 16, More...12 Night - Wonders of Cambodia, Vietnam & the Mekong
Starting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
River Cruises that depart from Asia/Far East: Cambodia: Siem Reap
River Cruises that visit Siem Reap
See all Cruises that depart from Siem Reap
Tonle Sap Lake Cruises
Click on a cruise ship itinerary sailing from Siem Reap (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Siem Reap), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
10 Night - Enchanting Mekong and Siem ReapStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Prek KDam / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation
2026 Sails: Feb 4, Feb 18, More...
12 Night - Riches of the Mekong with Siem Reap Pre-Cruise and Ho Chi Minh City Post-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 13, Apr 10, Apr 24, 2027: Jan 1, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...
10 Night - Riches of the Mekong with Siem Reap Pre-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 13, Apr 10, Apr 24, 2027: Jan 1, Jan 29, Feb 12, Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, More...
9 Night - Riches of the Mekong with Ho Chi Minh Post-CruiseStarting in Siem Reap, Kampong Cham, Angkor Ban, Oknhatey Village, Phnom Penh, Oudong, Phnom Penh, Border Crossing, Tan Chau, Sa Dec, Cai Be, My Tho, Ho Chi Minh City
2026 Sails: Feb 16, Apr 13, Apr 27, 2027: Jan 4, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, More...
12 Night - Fascinating Vietnam, Cambodia & the Mekong River (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City
2026 Sails: Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 19, Nov 2, Nov 16, Nov 30, More...
15 Night - Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound)Starting in Siem Reap, Cambodia, Siem Reap, Siem Reap / Phnom Penh (Embarkation), Wat Hanchey / Angkor Ban, Kampong Tralach / Konpong Louang / Phnom Penh, Phnom Penh, Border Crossing / Chau Doc, Vietnam, Long Khanh / Cu Lao Gieng, Vinh Long, Ho Chi Minh City (Disembarkation), Ho Chi Minh City Excursion to Cu Chi Tunnels, Ho Chi Minh City / Bangkok, Thailand, Bangkok
2026 Sails: Apr 6, Apr 20, Aug 10, Aug 24, Sep 7, Sep 21, Oct 19, Nov 2, Nov 16, Nov 30, More...
12 Night - Treasures of the MekongStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City, Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Oct 31, Nov 14, Nov 28, More...
10 Night - Luxury Mekong and Temple Discovery CruiseStarting in Siem Reap, Siem Reap / Mekong Cruise, Wat Hanchey / Kampong Cham, Angkor Ban / Silk Island / Phnom Penh, Phnom Penh, Phnom Penh / Border Crossing / Tan Chau, Tan Chau, Sa Dec / Cai Be, Mekong Cruise / Ho Chi Minh City
2026 Sails: May 9, Sep 19, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, More...
14 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Peam Chi Korng / Mekong Cruise, Angkor Ban / Phnom Penh, Phnom Penh, Phnom Penh / Cross Cambodia / Vietnam Border, Tan Chau, An Long / Gieng Island, My An Hung / Sa Dec, Ben Tre, Cho Gao canal / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Aug 18, Sep 5, Dec 16, More...
12 Night - Wonders of Cambodia, Vietnam & the MekongStarting in Arrive Siem Reap, Siem Reap, Siem Reap / Rokar Koang / Mekong Cruise, Kampong Tralach / Oudong / Phnom Penh, Phnom Penh, Cross Vietnam / Cambodia Border / Tan Chau, Gieng Island / My An Hung, Sa Dec / Cai Be, My Tho / Ho Chi Minh City, Ho Chi Minh City Disembarkation, Ho Chi Minh City, Depart Ho Chi Minh City
2026 Sails: Sep 23, Oct 7, Nov 4, Nov 18, Dec 2, 2027: Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, May 12, More...
