Main River Cruises

River Cruises sailing on the Main River

Click on a cruise ship itinerary sailing on the Main River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Main River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Main River also sail:
Aare River : Amstel River : Cibin River : Corrib River : Dambovita River : Danube River : Drava River : Elbe River : Inn River : Isar River : Lake Brienz : Lake Geneva : Lek River : Liffey River : Limmat River : Ljubljanica River : Loch Lomond : Moselle River : Neckar River : Ness River : Netherlands Waterways : Ouse River : Reuss River : Rhine River : Rhone River : Roth River : Salzach River : Sava River : Scheldt River : Seine River : Senne River : Spree River : Vltava River : Volkach River : Water of Leith River

7 Night - Legendary Rhine & Moselle
Starting in Frankfurt Airport / Mainz (Wiesbaden), Rudesheim, Bernkastel, Trier (Schweich), Cochem, Koblenz, Mainz, Mainz (Wiesbaden) Frankfurt
2026 Sails: Jul 4, More...

Viking River, Viking Bragi

14 Night - Grand European Tour
Starting in Amsterdam, Kinderdijk, Scenic Sailing Waal and Merwede, Cologne, Koblenz, Middle Rhine Scenic Sailing, Miltenberg, Scenic Sailing Main River, Wurzburg, Bamberg, Main-Danube Canal, Nuremberg, Regensburg, Passau, Melk, Scenic Sailing Wachau Valley, Krems, Vienna, Budapest
2026 Sails: Jul 4, Oct 24, More...

Scenic Luxury, Scenic Jasper

14 Night - Jewels of Europe
Starting in Amsterdam, Cologne / Bonn, Rhine Gorge / Rudesheim, Miltenberg / Wertheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Passau / Schlogen, Durnstein / Krems, Vienna, Budapest
2026 Sails: Jul 7, Aug 18, More...

Scenic Luxury, Scenic Opal

14 Night - Jewels of Europe
Starting in Budapest, Vienna, Krems / Durnstein, Brandstatt / Passau, Regensburg, Nuremberg, Bamberg, Wurzburg, Wertheim / Miltenberg, Rudesheim / Rhine Gorge / Bonn, Cologne, Amsterdam
2026 Sails: Jul 7, Aug 18, Oct 27, More...

AmaWaterways, AmaCerto

7 Night - Europe's Rivers & Castles (Loyalty Cruise)
Starting in Nuremberg, Bamberg, Wurzburg, Wertheim, Lahnstein, Cochem, Wasserbillig, Luxembourg
2026 Sails: Jul 8, More...

Avalon Waterways, Avalon Imagery II

9 Night - Reflections On the Rhine (Southbound)
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Nijmegen, Cologne, Germany, Rhine Gorge / Rudesheim, Frankfurt, Speyer Excursion to Heidelberg, Strasbourg, France, Breisach, Germany Excursion to Black Forest, Basel, Switzerland (Disembarkation)
2026 Sails: Jul 8, Oct 2, More...

Viking River Tours, Viking Alsvin Tours

11 Night - Cities of Light
Starting in Paris, Trier, Bernkastel, Cochem, Koblenz, Middle Rhine Scenic Sailing, Heidelberg, Scenic Sailing : Main River, Spessart, Wurzburg, Bamberg, Prague
2026 Sails: Jul 8, Aug 5, Oct 28, Nov 11, 2027: Mar 3, Mar 17, Apr 28, May 12, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, 2028: Mar 1, Apr 26, May 24, Jun 7, More...

Avalon Waterways, Avalon Expression

14 Night - Magnificent Europe
Starting in Amsterdam, Holland (Embarkation), Amsterdam, Cologne, Germany, Rhine Gorge / Rudesheim, Miltenberg, Wurzburg, Volkach, Bamberg, Nuremberg, Regensburg, Passau, Melk / Wachau Valley, Vienna, Budapest, Hungary, Budapest (Disembarkation)
2026 Sails: Jul 9, Sep 10, More...

Avalon Waterways, Avalon Impression

Riviera River, MS George Eliot

7 Night - Medieval Germany : Bavaria and the Romantic Road
Starting in Mainz, Germany, Miltenberg, Germany, Main River, Wurzburg, Germany, Main River, Mainz, Germany
2026 Sails: Jul 9, Aug 26, Sep 2, Sep 9, Sep 16, Sep 23, More...

More =>