Spain Cruises

Cruises that visit Europe: Spain

Cruises that depart from Spain

See all River Cruises that visit Spain

Click on a cruise ship itinerary that visits Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome)
2026 Sails: Jun 19, More...

MSC Cruises, MSC Grandiosa

7 Night - Mediterranean
Starting in Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain, Cannes (Cote D Azur), France, Genoa (Portofino), Italy, La Spezia (Cinque Terre), Italy, Civitavecchia (Rome), Italy, Palma De Mallorca (Balearic Islands), Spain
2026 Sails: Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, More...

MSC Cruises, MSC Opera

10 Night - Mediterranean
Starting in Alicante, Spain, Mahon, Spain, Olbia, Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Malaga (Granada), Spain, Cadiz (Seville), Spain, Lisbon (Cascais), Portugal, Alicante, Spain
2026 Sails: Jun 19, Jun 29, Jul 9, Jul 19, Aug 8, Aug 18, Aug 28, Sep 7, More...

MSC Cruises, MSC Splendida

7 Night - Mediterranean
Starting in La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy, Palermo (Monreale), Italy, La Valletta, Malta
2026 Sails: Jun 19, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, Nov 6, More...

Regent Seven Seas, Seven Seas Splendor

10 Night - Classic Iberia
Starting in Athens (Piraeus), Cruising the Mediterranean Sea, Valletta, Trapani (Sicily), La Goulette, Cruising the Mediterranean Sea, Palma De Mallorca, Almeria, Cadiz, Portimao, Lisbon
2026 Sails: Jun 19, More...

Regent Seven Seas, Seven Seas Splendor

17 Night - Mediterranean Mystique
Starting in Athens (Piraeus), Cruising the Mediterranean Sea, Valletta, Trapani (Sicily), La Goulette, Cruising the Mediterranean Sea, Palma De Mallorca, Almeria, Cadiz, Portimao, Lisbon, Cadiz, Tangier, Cruising the Mediterranean Sea, Barcelona, Mahon, Minorca, Provence (Marseille), Monte Carlo
2026 Sails: Jun 19, More...

AmaWaterways, AmaVida

7 Night - Flavors of Portugal & Spain
Starting in Vega de Terron, Barca dAlva, Pinhao, Regua, Entre-os-Rios, Porto
2026 Sails: Jun 20, Nov 7, 2027: Mar 27, Nov 6, More...

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia, Civitavecchia (Rome)
2026 Sails: Jun 20, Jul 4, Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Jun 20, More...

MSC Cruises, MSC Virtuosa

7 Night - Northern Europe
Starting in Southampton (London), United Kingdom, La Rochelle, France, Bilbao, Spain, La Coruna (Santiago De Compostela), Spain, Cherbourg (Mont Saint-Michel), France, Southampton (London), United Kingdom
2026 Sails: Jun 20, Sep 5, More...

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