South Carolina Cruises
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Related areas: Beaufort : Charleston : Hilton Head Island
15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Apr 17, 2028: Apr 22, More...
15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, More...
15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, More...
16 Night - Spotlight with Southern Living
Starting in Miami, Cruising the Old Bahama Channel, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Bonaire (Kralendijk), St Georges, Castries, Gustavia, San Juan, Cruising the Atlantic Ocean, Charleston, Cruising the Atlantic Ocean, New York
2026 Sails: Jun 13, More...
22 Night - Gaelic & Icelandic Sagas
Starting in London (Southampton), Falmouth (Cornwall), Dublin (Dun Laoghaire), Cork (Cobh), Belfast, Glasgow (Greenock), Torshavn, Faroe Islands, Akureyri, Isafjordur, Reykjavik, Halifax, New York, Charleston, Miami
2026 Sails: Jun 14, More...
11 Night - Pre Philadelphia Cruisetour
Starting in At Hotel, Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Aug 25, More...9 Night - Bermuda
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Aug 27, More...
14 Night - Canada & East Coast Explorer
Starting in Toronto, Ontario, Scenic Sailing St Lawrence Seaway Locks, Trois-Rivieres, Quebec, Quebec City, Quebec, Scenic Sailing St Lawrence River, Cap-Aux-Meules, Quebec, Cape Breton Island (Louisbourg), Nova Scotia, Lunenburg, Nova Scotia, Sail the Atlantic Ocean, Norfolk, Virginia, Sail the Atlantic Ocean, Charleston, South Carolina, Sail the Atlantic Ocean, Fort Lauderdale, Florida
2026 Sails: Oct 9, More...
19 Night - Maple Explorer - Tour 2B
Starting in Toronto, Canada, Ottawa, Canada, Montebello, Canada, Montreal, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, Boston, Massachusetts, Newport, Rhode Island, New York City (Manhattan or Brooklyn), New York, Charleston, South Carolina, Fort Lauderdale, Florida
2026 Sails: Oct 18, More...14 Night - Canada & Colonial America
Starting in Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, Boston, Massachusetts, Newport, Rhode Island, New York City (Manhattan or Brooklyn), New York, Charleston, South Carolina, Fort Lauderdale, Florida
2026 Sails: Oct 23, More...
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Beaufort : Charleston : Hilton Head Island
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: Apr 17, 2028: Apr 22, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 13, More...
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, More...
16 Night - Spotlight with Southern LivingStarting in Miami, Cruising the Old Bahama Channel, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Bonaire (Kralendijk), St Georges, Castries, Gustavia, San Juan, Cruising the Atlantic Ocean, Charleston, Cruising the Atlantic Ocean, New York
2026 Sails: Jun 13, More...
Deal link -> Special
22 Night - Gaelic & Icelandic SagasStarting in London (Southampton), Falmouth (Cornwall), Dublin (Dun Laoghaire), Cork (Cobh), Belfast, Glasgow (Greenock), Torshavn, Faroe Islands, Akureyri, Isafjordur, Reykjavik, Halifax, New York, Charleston, Miami
2026 Sails: Jun 14, More...
11 Night - Pre Philadelphia CruisetourStarting in At Hotel, Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Aug 25, More...
9 Night - BermudaStarting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Aug 27, More...
14 Night - Canada & East Coast ExplorerStarting in Toronto, Ontario, Scenic Sailing St Lawrence Seaway Locks, Trois-Rivieres, Quebec, Quebec City, Quebec, Scenic Sailing St Lawrence River, Cap-Aux-Meules, Quebec, Cape Breton Island (Louisbourg), Nova Scotia, Lunenburg, Nova Scotia, Sail the Atlantic Ocean, Norfolk, Virginia, Sail the Atlantic Ocean, Charleston, South Carolina, Sail the Atlantic Ocean, Fort Lauderdale, Florida
2026 Sails: Oct 9, More...
19 Night - Maple Explorer - Tour 2BStarting in Toronto, Canada, Ottawa, Canada, Montebello, Canada, Montreal, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, Boston, Massachusetts, Newport, Rhode Island, New York City (Manhattan or Brooklyn), New York, Charleston, South Carolina, Fort Lauderdale, Florida
2026 Sails: Oct 18, More...
14 Night - Canada & Colonial AmericaStarting in Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, Boston, Massachusetts, Newport, Rhode Island, New York City (Manhattan or Brooklyn), New York, Charleston, South Carolina, Fort Lauderdale, Florida
2026 Sails: Oct 23, More...
