South Carolina Cruises
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Related areas: Beaufort : Charleston : Hilton Head Island
15 Night - East Coast Inland Passage Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, 2027: Jun 18, More...
9 Night - Pre Philadelphia Cruisetour
Starting in At Hotel, Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Jun 9, Jun 16, Jun 23, More...
16 Night - Spotlight with Southern Living
Starting in Miami, Cruising the Old Bahama Channel, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Bonaire (Kralendijk), St Georges, Castries, Gustavia, San Juan, Cruising the Atlantic Ocean, Charleston, Cruising the Atlantic Ocean, New York
2026 Sails: Jun 13, More...
22 Night - Gaelic & Icelandic Sagas
Starting in London (Southampton), Falmouth (Cornwall), Dublin (Dun Laoghaire), Cork (Cobh), Belfast, Glasgow (Greenock), Torshavn, Faroe Islands, Akureyri, Isafjordur, Reykjavik, Halifax, New York, Charleston, Miami
2026 Sails: Jun 14, More...
11 Night - Chairman's Voyage : America's 250Th Anniversary Cruise
Starting in New York, Wilmington, Delaware / Chesapeake and Delaware Canal, Baltimore, Maryland, Yorktown, Virginia, Wilmington, North Carolina, Charleston, South Carolina, Miami, Florida, Key West, Florida, Nassau, Bahamas
2026 Sails: Oct 5, More...
14 Night - Canada & East Coast Explorer
Starting in Toronto, Ontario, Scenic Sailing St Lawrence Seaway Locks, Trois-Rivieres, Quebec, Quebec City, Quebec, Scenic Sailing St Lawrence River, Cap-Aux-Meules, Quebec, Cape Breton Island (Louisbourg), Nova Scotia, Lunenburg, Nova Scotia, Sail the Atlantic Ocean, Norfolk, Virginia, Sail the Atlantic Ocean, Charleston, South Carolina, Sail the Atlantic Ocean, Fort Lauderdale, Florida
2026 Sails: Oct 9, More...15 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 26, More...
15 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 31, 2027: Nov 8, More...
15 Night - East Coast Inland Passage Cruise
Starting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 3, 2027: Oct 25, More...8 Night - Southeast Sea Islands Cruise
Starting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 9, Feb 23, Nov 25, Dec 9, Dec 23, More...
Cruises that visit North America: United States: South Carolina
Cruises that depart from South Carolina
See all River Cruises that visit South Carolina
Click on a cruise ship itinerary that visits South Carolina (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South Carolina), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Beaufort : Charleston : Hilton Head Island
15 Night - East Coast Inland Passage CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island, GA, St Simons Island, GA, Savannah, GA, Hilton Head, SC, Beaufort, SC, Charleston, SC, Day of Cruising, Wilmington, NC, Beaufort, NC / Morehead City, NC, Kitty Hawk, NC, Norfolk, Va, St Michaels, MD, Washington, DC
2026 Sails: May 22, 2027: Jun 18, More...
9 Night - Pre Philadelphia CruisetourStarting in At Hotel, Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Charleston, SC, Philadelphia, Pa
2026 Sails: Jun 9, Jun 16, Jun 23, More...
16 Night - Spotlight with Southern LivingStarting in Miami, Cruising the Old Bahama Channel, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Bonaire (Kralendijk), St Georges, Castries, Gustavia, San Juan, Cruising the Atlantic Ocean, Charleston, Cruising the Atlantic Ocean, New York
2026 Sails: Jun 13, More...
22 Night - Gaelic & Icelandic SagasStarting in London (Southampton), Falmouth (Cornwall), Dublin (Dun Laoghaire), Cork (Cobh), Belfast, Glasgow (Greenock), Torshavn, Faroe Islands, Akureyri, Isafjordur, Reykjavik, Halifax, New York, Charleston, Miami
2026 Sails: Jun 14, More...
11 Night - Chairman's Voyage : America's 250Th Anniversary CruiseStarting in New York, Wilmington, Delaware / Chesapeake and Delaware Canal, Baltimore, Maryland, Yorktown, Virginia, Wilmington, North Carolina, Charleston, South Carolina, Miami, Florida, Key West, Florida, Nassau, Bahamas
2026 Sails: Oct 5, More...
14 Night - Canada & East Coast ExplorerStarting in Toronto, Ontario, Scenic Sailing St Lawrence Seaway Locks, Trois-Rivieres, Quebec, Quebec City, Quebec, Scenic Sailing St Lawrence River, Cap-Aux-Meules, Quebec, Cape Breton Island (Louisbourg), Nova Scotia, Lunenburg, Nova Scotia, Sail the Atlantic Ocean, Norfolk, Virginia, Sail the Atlantic Ocean, Charleston, South Carolina, Sail the Atlantic Ocean, Fort Lauderdale, Florida
2026 Sails: Oct 9, More...
15 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 26, More...
15 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Oct 31, 2027: Nov 8, More...
15 Night - East Coast Inland Passage CruiseStarting in Baltimore, MD, Day of Cruising, St Michaels, MD, Norfolk, Va, Kitty Hawk, NC, Beaufort, NC / Morehead City, NC, Wilmington, NC, Day of Cruising, Charleston, SC, Beaufort, SC, Hilton Head, SC, Savannah, GA, St Simons Island, GA, Jekyll Island, GA, Amelia Island / Fernandina Beach, FL, Amelia Island, FL
2026 Sails: Nov 3, 2027: Oct 25, More...
8 Night - Southeast Sea Islands CruiseStarting in Amelia Island, FL, Day of Cruising, Jekyll Island / St Simons Island, GA, Cruising Intracoastal Waterway, Savannah, GA, Hilton Head Island, SC, Beaufort, SC, Charleston, SC
2026 Sails: Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 27, Feb 10, Feb 24, Mar 10, Nov 22, Dec 6, Dec 20, 2028: Feb 9, Feb 23, Nov 25, Dec 9, Dec 23, More...
