Rome Cruises
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
11 Night - Best of the Mediterranean Cruise : Monte Carlo, Rome & Sorrento
Starting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Sorrento, Catania, (Sicily), Crotone, Kotor, Koper, Venice (Fusina)
2026 Sails: Sep 13, More...31 Night - Mediterranean Cruise : Italy, Croatia & Greece
Starting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Sorrento, Catania, (Sicily), Crotone, Kotor, Koper, Venice (Fusina), Zadar, Sibenik, Korcula, Dubrovnik, Croatia, Kotor, Corfu, Chania, Crete, Athens (Piraeus), Chios, Istanbul, Canakkale (Kepez), Thessaloniki, Volos, Syros, Patmos, Nafplio, Athens (Piraeus)
2026 Sails: Sep 13, More...
27 Night - Highlights of Spain - Tour 2C
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 13, More...20 Night - Highlights of Spain - Tour 2B
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 13, More...
21 Night - Istanbul, Greek Islands and Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey, Dardanelles Strait, Turkey (Transit), Piraeus (tours to Athens), Greece, Souda Bay (for Chania), Crete, Greece, Katakolon (tours to Olympia), Greece, Messina Strait, Italy (Transit), Civitavecchia (tours to Rome), Italy
2026 Sails: Sep 14, More...14 Night - Istanbul, Greek Islands and Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey
2026 Sails: Sep 14, More...
14 Night - An Extended Journey of Vibrant Cities & Coastal Delights
Starting in Barcelona, Porto Cervo (Sardinia), Ajaccio (Corsica), Saint-Tropez, Portofino, Livorno (Florence), Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona
2026 Sails: Sep 14, More...
11 Night - Epicurean Spotlight On Wine
Starting in Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Monte Carlo, Cruising the Ligurian Sea, Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Sep 18, More...21 Night - The Best of the Mediterranean
Starting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 19, More...14 Night - Mediterranean with Greece, Italy & Turkey
Starting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 19, More...
Cruises that visit Mediterranean: Italy: Rome
Cruises that depart from Rome
See all River Cruises that visit Rome
Click on a cruise ship itinerary that visits Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
11 Night - Best of the Mediterranean Cruise : Monte Carlo, Rome & SorrentoStarting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Sorrento, Catania, (Sicily), Crotone, Kotor, Koper, Venice (Fusina)
2026 Sails: Sep 13, More...
31 Night - Mediterranean Cruise : Italy, Croatia & GreeceStarting in Barcelona, Provence (Marseille), Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Sorrento, Catania, (Sicily), Crotone, Kotor, Koper, Venice (Fusina), Zadar, Sibenik, Korcula, Dubrovnik, Croatia, Kotor, Corfu, Chania, Crete, Athens (Piraeus), Chios, Istanbul, Canakkale (Kepez), Thessaloniki, Volos, Syros, Patmos, Nafplio, Athens (Piraeus)
2026 Sails: Sep 13, More...
27 Night - Highlights of Spain - Tour 2CStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 13, More...
20 Night - Highlights of Spain - Tour 2BStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 13, More...
21 Night - Istanbul, Greek Islands and MediterraneanStarting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey, Dardanelles Strait, Turkey (Transit), Piraeus (tours to Athens), Greece, Souda Bay (for Chania), Crete, Greece, Katakolon (tours to Olympia), Greece, Messina Strait, Italy (Transit), Civitavecchia (tours to Rome), Italy
2026 Sails: Sep 14, More...
14 Night - Istanbul, Greek Islands and MediterraneanStarting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey
2026 Sails: Sep 14, More...
14 Night - An Extended Journey of Vibrant Cities & Coastal DelightsStarting in Barcelona, Porto Cervo (Sardinia), Ajaccio (Corsica), Saint-Tropez, Portofino, Livorno (Florence), Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona
2026 Sails: Sep 14, More...
11 Night - Epicurean Spotlight On WineStarting in Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Monte Carlo, Cruising the Ligurian Sea, Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Sep 18, More...
21 Night - The Best of the MediterraneanStarting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 19, More...
14 Night - Mediterranean with Greece, Italy & TurkeyStarting in Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 19, More...
