Portobelo Cruises
Cruises that visit Central America: Panama: Portobelo
7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Panama City, Panama / Disembark Ship
2026 Sails: Oct 31, 2027: Nov 12, Nov 19, More...7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Disembark Ship, Cispata Bay / Sanguare Natural Reserve, Santa Cruz de Lorica / San Antero / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Panama City, Panama / Colon / Embark Ship
2026 Sails: Nov 7, More...7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Panama City, Panama / Disembark Ship, Portobelo, Guna Yala Archipelago, Capurgana and Sapzurro, Colombia, San Antero / Santa Cruz de Lorica / Tuchin, Sanguare Natural Reserve / Cispata Bay, Cartagena CO, Colombia / Embark Ship
2026 Sails: Nov 7, More...
12 Night - Panama, Colombia & Caribbean Islands
Starting in Fort-de-France, Marie-Galante, Pigeon Island Beach, Soufriere, Union Island, Mayreau Island, Bonaire, Santa Marta, Cartagena CO, San Blas Islands, Portobelo, Colon
2026 Sails: Dec 7, More...8 Night - Exploring Arenal Volcano, Pearl Islands and the Panama Canal
Starting in San Jose, Costa Rica / Arenal Volcano Area, Arenal Volcano Area, San Jose / Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2027 Sails: Jan 13, Jan 17, Jan 21, Nov 22, Nov 26, 2028: Jan 21, More...7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Portobelo, Crossing the Panama Canal, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Jan 15, More...
11 Night - Panama to Aruba
Starting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, Portobelo, Panama, San Blas Archipelago, Panama, Cartagena De Indias, Colombia, Santa Marta, Colombia, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba
2027 Sails: Jan 16, More...
Cruises that visit Central America: Panama: Portobelo
Click on a cruise ship itinerary that visits Portobelo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portobelo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Panama and Colombia : Exploring the Caribbean CoastStarting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Panama City, Panama / Disembark Ship
2026 Sails: Oct 31, 2027: Nov 12, Nov 19, More...
7 Night - Panama and Colombia : Exploring the Caribbean CoastStarting in Cartagena CO, Colombia / Disembark Ship, Cispata Bay / Sanguare Natural Reserve, Santa Cruz de Lorica / San Antero / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Panama City, Panama / Colon / Embark Ship
2026 Sails: Nov 7, More...
7 Night - Panama and Colombia : Exploring the Caribbean CoastStarting in Panama City, Panama / Disembark Ship, Portobelo, Guna Yala Archipelago, Capurgana and Sapzurro, Colombia, San Antero / Santa Cruz de Lorica / Tuchin, Sanguare Natural Reserve / Cispata Bay, Cartagena CO, Colombia / Embark Ship
2026 Sails: Nov 7, More...
12 Night - Panama, Colombia & Caribbean IslandsStarting in Fort-de-France, Marie-Galante, Pigeon Island Beach, Soufriere, Union Island, Mayreau Island, Bonaire, Santa Marta, Cartagena CO, San Blas Islands, Portobelo, Colon
2026 Sails: Dec 7, More...
8 Night - Exploring Arenal Volcano, Pearl Islands and the Panama CanalStarting in San Jose, Costa Rica / Arenal Volcano Area, Arenal Volcano Area, San Jose / Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2027 Sails: Jan 13, Jan 17, Jan 21, Nov 22, Nov 26, 2028: Jan 21, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Portobelo, Crossing the Panama Canal, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Jan 15, More...
11 Night - Panama to ArubaStarting in Balboa (Isla Flamenco), Panama, Panama Canal Transit, Portobelo, Panama, San Blas Archipelago, Panama, Cartagena De Indias, Colombia, Santa Marta, Colombia, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba
2027 Sails: Jan 16, More...
