Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 22, More...
16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2027 Sails: Sep 25, More...
14 Night - Journeys - Caribbean & Panama
Starting in Mobile, Al, Ocho Rios, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Mobile, Al
2027 Sails: Sep 26, More...
19 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Huatulco, Mexico, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2027 Sails: Sep 27, More...18 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 27, More...
17 Night - Panama Canal - Miami
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Fl
2027 Sails: Sep 30, More...
21 Night - Panama Canal
Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 2, More...20 Night - Panama Canal
Starting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 3, More...
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Seattle, Washington, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Port Canaveral (Orlando), Florida
2027 Sails: Oct 3, More...16 Night - Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 7, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 22, More...
16 Night - Journeys - Panama CanalStarting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2027 Sails: Sep 25, More...
14 Night - Journeys - Caribbean & PanamaStarting in Mobile, Al, Ocho Rios, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Mobile, Al
2027 Sails: Sep 26, More...
19 Night - Msc Grand VoyagesStarting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Huatulco, Mexico, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2027 Sails: Sep 27, More...
18 Night - Panama Canal - Ocean to OceanStarting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 27, More...
17 Night - Panama Canal - MiamiStarting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Fl
2027 Sails: Sep 30, More...
21 Night - Panama CanalStarting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 2, More...
20 Night - Panama CanalStarting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 3, More...
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, Seattle, Washington, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Port Canaveral (Orlando), Florida
2027 Sails: Oct 3, More...
16 Night - Panama CanalStarting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 7, More...
