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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



MSC Poesia Cruise Ship18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 23, More...
Oceania Insignia Cruise Ship10 Night - Canal & Coral Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
NCL Norwegian Joy Cruises15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...
NCL Norwegian Joy Cruises18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
RCL Serenade of the Seas Cruise Ship10 Night - Panama Canal Westward Cruise
Starting in Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 25, More...
HAL Volendam Cruise Ship14 Night - Grand World Voyage
Starting in San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: May 3, More...
Crown Princess Cruise Ship115 Night - World Cruise - Roundtrip Auckland
Starting in Auckland, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand
2026 Sails: May 6, More...
Crown Princess Cruise Ship117 Night - World Cruise - Sydney to Brisbane
Starting in Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Sydney AU, Brisbane, Australia
2026 Sails: May 10, More...
Crown Princess Cruise Ship115 Night - World Cruise - Roundtrip Sydney
Starting in Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Sydney AU
2026 Sails: May 10, More...
Silver Nova Cruises20 Night - Seattle to Miami
Starting in Seattle, Washington, San Diego, California, Cabo San Lucas (Baja California), Puntarenas, Panama Canal Transit, Cartagena CO, Miami, Fl
2026 Sails: May 11, More...


Panama Canal Cruises