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Palermo Cruises

Cruises that visit Mediterranean: Italy: Palermo

Cruises that depart from Palermo

See all River Cruises that visit Palermo

Click on a cruise ship itinerary that visits Palermo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Palermo), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Explora Journeys, EXPLORA I
EXPLORA I9 Night - A Journey Through the Artistic and Historic Spirit of Mediterranean Coastal Beauty
Starting in Barcelona, Marseille, Villefranche-Sur-Mer (Nice), Porto Santo Stefano (Argentario), Port of Naples, Palermo (Sicily), Ibiza, Palma De Mallorca, Barcelona
2026 Sails: Oct 12, More...
Explora Journeys, EXPLORA I
EXPLORA I20 Night - An Extended Journey Through Mediterranean Gems & Sun-Hazed Gateways
Starting in Barcelona, Marseille, Villefranche-Sur-Mer (Nice), Porto Santo Stefano (Argentario), Port of Naples, Palermo (Sicily), Ibiza, Palma De Mallorca, Barcelona, Alicante, Lisbon, Casablanca, Tangier, Malaga, Spain, Motril, Barcelona
2026 Sails: Oct 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean Roundtrip from Cagliari
Starting in Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona, Cagliari
2026 Sails: Oct 14, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit8 Night - Sail Away from Fall
Starting in Valletta, Syracuse IT, Sicily, Italy, Palermo, Sicily, Trapani, Sicily, Cagliari / Sardinia, Mahon / Menorca, Palma De Mallorca
2026 Sails: Oct 17, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 19, More...
Oceania Cruises, Oceania Sirena
Oceania Sirena10 Night - Havens of Italy & Spain
Starting in Monte Carlo, Portofino, Rome (Civitavecchia), Naples / Pompeii, Olbia / Porto Cervo (Sardinia), Palermo (Sicily), Ibiza, Alicante, Valencia, Barcelona (Tarragona)
2026 Sails: Oct 19, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox10 Night - Italy, Spain & Malta Cruise
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy, Naples, Italy, Valletta, Malta, Sicily (Palermo), Italy, Barcelona, Spain
2026 Sails: Oct 20, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean Roundtrip from Cagliari
Starting in Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona, Cagliari
2026 Sails: Oct 21, Oct 28, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, Cagliari, Palermo, Civitavecchia (Rome)
2026 Sails: Oct 23, Oct 30, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Cagliari, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Oct 24, Oct 31, More...

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Palermo Cruises