Palermo Cruises
Cruises that visit Mediterranean: Italy: Palermo
Cruises that depart from Palermo
23 Night - Mediterranean Constellation
Starting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jun 24, More...12 Night - Minarets & Mosaics
Starting in Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jul 5, More...
8 Night - French Riviera, Rome, Amalfi & Sicily
Starting in Barcelona, Spain, Provence (Marseille), France, Nice (Villafranche), France, Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Catania, Sicily, Italy, Palermo, Sicily, Italy, Barcelona, Spain
2026 Sails: Jul 11, More...
10 Night - Mediterranean Delights
Starting in Valletta, Malta, Mgarr, Malta, Porto Empedocle, Italy, Mazara del Vallo, Italy, Sidi Bou Said, Tunisia, Trapani, Italy, Palermo, Italy, Lipari, Italy, Giardini Naxos, Italy, Syracuse, Italy, Valletta, Malta
2026 Sails: Jul 20, More...
10 Night - Fusina to Civitavecchia
Starting in Fusina (Venice), Zadar, Split, Dubrovnik, Croatia, Bari, Kotor, Giardini Naxos (Sicily), Palermo, Sicily, Naples, Civitavecchia (Rome)
2026 Sails: Jul 21, More...
7 Night - Rome (Civitavecchia) / Rome (Civitavecchia)
Starting in Rome (Civitavecchia), Valletta, Trapani, Palermo, Sicily, Amalfi, Sorrento, Rome (Civitavecchia)
2026 Sails: Jul 24, More...
14 Night - Mediterranean & Adriatic with Total Solar Eclipse
Starting in Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Kotor, Montenegro, Dubrovnik, Croatia, Corfu, Greece, Sicily (Messina), Italy, Sicily (Palermo), Italy, Gibraltar, Alicante, Spain, Barcelona, Spain, Civitavecchia (for Rome), Italy
2026 Sails: Aug 4, More...
22 Night - European Explorer
Starting in London (Southampton), Bordeaux (Le Verdon), Biarritz (Saint-Jean-De-Luz), Gijon, Spain, Ferrol, Oporto, Lisbon, Seville (Cadiz), Malaga, Almeria, Alicante, Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 5, More...10 Night - Visions of Byzantium
Starting in Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...
8 Night - A Circumnavigation of Sicily - with Smithsonian Journeys
Starting in Valletta, Porto Empedocle, Sicily, Tunis, Trapani, Sicily, Palermo, Sicily, Lipari, Aeolian Islands, Sailing in front of Stromboli, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: Aug 29, 2027: May 10, More...
Cruises that visit Mediterranean: Italy: Palermo
Cruises that depart from Palermo
Click on a cruise ship itinerary that visits Palermo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Palermo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Deal link -> Special
23 Night - Mediterranean ConstellationStarting in Lisbon, Portimao, Seville (Cadiz), Barcelona (Tarragona), Toulon, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia), Amalfi / Positano, Gythion, Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jun 24, More...
Deal link -> Special
12 Night - Minarets & MosaicsStarting in Athens (Piraeus), Mykonos, Istanbul, Canakkale (Troy), Ephesus (Kusadasi), Marmaris, Heraklion (Crete), Tunis (La Goulette), Palermo (Sicily), Monte Carlo
2026 Sails: Jul 5, More...
8 Night - French Riviera, Rome, Amalfi & SicilyStarting in Barcelona, Spain, Provence (Marseille), France, Nice (Villafranche), France, Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Catania, Sicily, Italy, Palermo, Sicily, Italy, Barcelona, Spain
2026 Sails: Jul 11, More...
10 Night - Mediterranean DelightsStarting in Valletta, Malta, Mgarr, Malta, Porto Empedocle, Italy, Mazara del Vallo, Italy, Sidi Bou Said, Tunisia, Trapani, Italy, Palermo, Italy, Lipari, Italy, Giardini Naxos, Italy, Syracuse, Italy, Valletta, Malta
2026 Sails: Jul 20, More...
10 Night - Fusina to CivitavecchiaStarting in Fusina (Venice), Zadar, Split, Dubrovnik, Croatia, Bari, Kotor, Giardini Naxos (Sicily), Palermo, Sicily, Naples, Civitavecchia (Rome)
2026 Sails: Jul 21, More...
7 Night - Rome (Civitavecchia) / Rome (Civitavecchia)Starting in Rome (Civitavecchia), Valletta, Trapani, Palermo, Sicily, Amalfi, Sorrento, Rome (Civitavecchia)
2026 Sails: Jul 24, More...
14 Night - Mediterranean & Adriatic with Total Solar EclipseStarting in Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Kotor, Montenegro, Dubrovnik, Croatia, Corfu, Greece, Sicily (Messina), Italy, Sicily (Palermo), Italy, Gibraltar, Alicante, Spain, Barcelona, Spain, Civitavecchia (for Rome), Italy
2026 Sails: Aug 4, More...
22 Night - European ExplorerStarting in London (Southampton), Bordeaux (Le Verdon), Biarritz (Saint-Jean-De-Luz), Gijon, Spain, Ferrol, Oporto, Lisbon, Seville (Cadiz), Malaga, Almeria, Alicante, Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 5, More...
10 Night - Visions of ByzantiumStarting in Barcelona, Palermo (Sicily), Syracuse (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...
8 Night - A Circumnavigation of Sicily - with Smithsonian JourneysStarting in Valletta, Porto Empedocle, Sicily, Tunis, Trapani, Sicily, Palermo, Sicily, Lipari, Aeolian Islands, Sailing in front of Stromboli, Taormina, Sicily, Syracuse, Sicily, Valletta
2026 Sails: Aug 29, 2027: May 10, More...
