Louisville Cruises
Cruises that visit North America: United States: Kentucky: Louisville
Cruises that depart from Louisville
See all River Cruises that visit Louisville
15 Night - Grand Ohio River Cruise
Starting in St Louis, MO, Cruising the Mississippi River, Paducah, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Louisville, KY, Madison, IN, Cincinnati, OH, Day of Cruising, Maysville, KY, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jun 19, 2027: Jul 2, More...
11 Night - Mississippi River Gateway Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Day of River Cruising, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of River Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2026 Sails: Jun 22, More...8 Night - Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 3, Jul 17, More...8 Night - Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 10, Jul 24, Aug 7, More...15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Jul 31, 2027: Jul 16, More...15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Aug 21, More...
14 Night - Bayous, Blues & Bluegrass
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...7 Night - Mississippi & Ohio River Explorer
Starting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 8, Nov 2, More...14 Night - Bayous, Blues & Bluegrass
Starting in Louisville, Kentucky, Owensboro, Kentucky, Henderson, Kentucky, Paducah, Kentucky, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2027 Sails: Jun 15, Nov 9, More...7 Night - Mississippi & Ohio River Explorer
Starting in Louisville, Kentucky, Owensboro, Kentucky, Henderson, Kentucky, Paducah, Kentucky, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2027 Sails: Jun 15, Nov 9, More...
Cruises that visit North America: United States: Kentucky: Louisville
Cruises that depart from Louisville
See all River Cruises that visit Louisville
Click on a cruise ship itinerary that visits Louisville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisville), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Grand Ohio River CruiseStarting in St Louis, MO, Cruising the Mississippi River, Paducah, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Louisville, KY, Madison, IN, Cincinnati, OH, Day of Cruising, Maysville, KY, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jun 19, 2027: Jul 2, More...
11 Night - Mississippi River Gateway CruiseStarting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Day of River Cruising, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of River Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2026 Sails: Jun 22, More...
8 Night - Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 3, Jul 17, More...
8 Night - Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Wheeling, WV, Marietta, OH, Day of Cruising, Cincinnati, OH, Madison, IN, Louisville, KY
2026 Sails: Jul 10, Jul 24, Aug 7, More...
15 Night - Grand Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Jul 31, 2027: Jul 16, More...
15 Night - Grand Ohio River CruiseStarting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Aug 21, More...
14 Night - Bayous, Blues & BluegrassStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...
7 Night - Mississippi & Ohio River ExplorerStarting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 8, Nov 2, More...
14 Night - Bayous, Blues & BluegrassStarting in Louisville, Kentucky, Owensboro, Kentucky, Henderson, Kentucky, Paducah, Kentucky, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2027 Sails: Jun 15, Nov 9, More...
7 Night - Mississippi & Ohio River ExplorerStarting in Louisville, Kentucky, Owensboro, Kentucky, Henderson, Kentucky, Paducah, Kentucky, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2027 Sails: Jun 15, Nov 9, More...
