Istanbul Cruises
Cruises that visit Mediterranean: Turkey: Istanbul
Cruises that depart from Istanbul
See all River Cruises that visit Istanbul
42 Night - Western Mediterranean from Valletta to Santa Cruz de Tenerife
Starting in Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 19, More...31 Night - Western Mediterranean from Valletta to Athens (Piraeus)
Starting in Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 19, More...
12 Night - Beauty Under the Stars
Starting in Valletta, Cruising the Mediterranean Sea, Catania (Sicily), Gallipoli, Dubrovnik, Croatia, Kotor, Katakolon, Cruising the Aegean Sea, Istanbul, Mytilini (Lesbos), Kusadasi, Santorini, Athens (Piraeus)
2026 Sails: Oct 20, More...
7 Night - Ancient Mediterranean Treasures
Starting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Oct 21, More...
10 Night - Glamorous Grecian Nights
Starting in Athens (Piraeus), Cruising the Sea of Crete, Heraklion (Crete), Cruising the Sea of Crete, Rhodes, Cruising the Aegean Sea, Istanbul
2026 Sails: Oct 24, More...
11 Night - Athens to Athens
Starting in Athens (Piraeus), Santorini, Kusadasi, Istanbul, Volos, Thessaloniki, Syros, Heraklion, Athens (Piraeus)
2026 Sails: Oct 26, More...
10 Night - Athens to Athens
Starting in Athens (Piraeus), Mykonos, Volos, Thessaloniki, Istanbul, Rhodes, Santorini, Athens (Piraeus)
2026 Sails: Oct 28, More...32 Night - Western Mediterranean from Heraklion to Santa Cruz de Tenerife
Starting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 29, More...21 Night - Western Mediterranean from Heraklion to Athens (Piraeus)
Starting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 29, More...42 Night - Western Mediterranean from Heraklion to Southampton
Starting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Oct 29, More...
Cruises that visit Mediterranean: Turkey: Istanbul
Cruises that depart from Istanbul
See all River Cruises that visit Istanbul
Click on a cruise ship itinerary that visits Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.
42 Night - Western Mediterranean from Valletta to Santa Cruz de TenerifeStarting in Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 19, More...
31 Night - Western Mediterranean from Valletta to Athens (Piraeus)Starting in Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 19, More...
12 Night - Beauty Under the StarsStarting in Valletta, Cruising the Mediterranean Sea, Catania (Sicily), Gallipoli, Dubrovnik, Croatia, Kotor, Katakolon, Cruising the Aegean Sea, Istanbul, Mytilini (Lesbos), Kusadasi, Santorini, Athens (Piraeus)
2026 Sails: Oct 20, More...
7 Night - Ancient Mediterranean TreasuresStarting in Istanbul, Troy (Canakkale), Ephesus (Kusadasi), Rhodes, Crete (Heraklion), Athens (Piraeus)
2026 Sails: Oct 21, More...
10 Night - Glamorous Grecian NightsStarting in Athens (Piraeus), Cruising the Sea of Crete, Heraklion (Crete), Cruising the Sea of Crete, Rhodes, Cruising the Aegean Sea, Istanbul
2026 Sails: Oct 24, More...
11 Night - Athens to AthensStarting in Athens (Piraeus), Santorini, Kusadasi, Istanbul, Volos, Thessaloniki, Syros, Heraklion, Athens (Piraeus)
2026 Sails: Oct 26, More...
10 Night - Athens to AthensStarting in Athens (Piraeus), Mykonos, Volos, Thessaloniki, Istanbul, Rhodes, Santorini, Athens (Piraeus)
2026 Sails: Oct 28, More...
32 Night - Western Mediterranean from Heraklion to Santa Cruz de TenerifeStarting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 29, More...
21 Night - Western Mediterranean from Heraklion to Athens (Piraeus)Starting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 29, More...
42 Night - Western Mediterranean from Heraklion to SouthamptonStarting in Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Oct 29, More...
