Istanbul Cruises
Cruises that visit Mediterranean: Turkey: Istanbul
Cruises that depart from Istanbul
See all River Cruises that visit Istanbul
14 Night - Istanbul and Greek Islands
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey, Dardanelles Strait, Turkey (Transit), Piraeus (tours to Athens), Greece, Souda Bay (for Chania), Crete, Greece, Katakolon (tours to Olympia), Greece, Messina Strait, Italy (Transit), Civitavecchia (tours to Rome), Italy
2026 Sails: Sep 21, More...
10 Night - Mysteries & Marvels
Starting in Athens (Piraeus), Gythion, Katakolon, Cruising the Aegean Sea, Kotor, Hvar, Cruising the Mediterranean Sea, Mykonos, Kusadasi, Istanbul
2026 Sails: Sep 22, More...
10 Night - Adriatic Allure : Croatia, Greek Isles & Istanbul
Starting in Trieste (Venice), Italy, Rijeka, Croatia, Split, Croatia, Thira (Santorini), Greece, Bodrum, Turkey, Kusadasi (Ephesus), Turkey, Istanbul, Turkey, Cruising the Dardanelles, Piraeus (Athens), Greece
2026 Sails: Sep 23, More...21 Night - Croatia, Greece & Istanbul Collectors' Voyage
Starting in Trieste (Venice), Italy, Rijeka, Croatia, Split, Croatia, Thira (Santorini), Greece, Bodrum, Turkey, Kusadasi (Ephesus), Turkey, Istanbul, Turkey, Cruising the Dardanelles, Piraeus (Athens), Greece, Nafplion, Greece, Istanbul, Turkey, Kusadasi (Ephesus), Turkey, Thira (Santorini), Greece, Rhodes, Greece, Souda (Chania), Greece, Piraeus (Athens), Greece
2026 Sails: Sep 23, More...
19 Night - Cruise & Rail : Slovenia, Venice, Istanbul & the Balkans
Starting in Ljubljana, Ljubljana (Lake Bled), Ljubljana (Karst), Transfer to Venice, Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Pula, Rijeka, Sarajevo, Mostar, Belgrade, Sofia, Plovdiv, Istanbul
2026 Sails: Sep 24, 2027: Apr 29, More...
11 Night - Mediterranean with Greek Isles & Turkey
Starting in Athens (Piraeus), Greece, Santorini, Greece, Kusadasi, Turkey (for Ephesus), Istanbul, Turkey, Rhodes, Greece, Sicily (Messina), Italy, Valletta, Malta, Civitavecchia (for Rome), Italy
2026 Sails: Sep 25, More...
61 Night - Western Mediterranean from Southampton to Santa Cruz de Tenerife
Starting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Sep 30, More...50 Night - Western Mediterranean from Southampton to Athens (Piraeus)
Starting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Sep 30, More...71 Night - Cruise Roundtrip from Southampton
Starting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Sep 30, More...
11 Night - Greece & Turkey Cruise : Athens, Istanbul & Syros
Starting in Athens (Piraeus), Chios, Istanbul, Canakkale (Kepez), Thessaloniki, Volos, Syros, Patmos, Nafplio, Athens (Piraeus)
2026 Sails: Oct 3, More...
Cruises that visit Mediterranean: Turkey: Istanbul
Cruises that depart from Istanbul
See all River Cruises that visit Istanbul
Click on a cruise ship itinerary that visits Istanbul (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Istanbul), please visit: Cruise Search or try our Virtual Cruise Advisor™.
14 Night - Istanbul and Greek IslandsStarting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Rhodes, Greece, Kusadasi (tours to Ephesus), Turkey, Dardanelles Strait, Turkey (Transit), Istanbul, Turkey, Dardanelles Strait, Turkey (Transit), Piraeus (tours to Athens), Greece, Souda Bay (for Chania), Crete, Greece, Katakolon (tours to Olympia), Greece, Messina Strait, Italy (Transit), Civitavecchia (tours to Rome), Italy
2026 Sails: Sep 21, More...
Deal link -> Special
10 Night - Mysteries & MarvelsStarting in Athens (Piraeus), Gythion, Katakolon, Cruising the Aegean Sea, Kotor, Hvar, Cruising the Mediterranean Sea, Mykonos, Kusadasi, Istanbul
2026 Sails: Sep 22, More...
10 Night - Adriatic Allure : Croatia, Greek Isles & IstanbulStarting in Trieste (Venice), Italy, Rijeka, Croatia, Split, Croatia, Thira (Santorini), Greece, Bodrum, Turkey, Kusadasi (Ephesus), Turkey, Istanbul, Turkey, Cruising the Dardanelles, Piraeus (Athens), Greece
2026 Sails: Sep 23, More...
21 Night - Croatia, Greece & Istanbul Collectors' VoyageStarting in Trieste (Venice), Italy, Rijeka, Croatia, Split, Croatia, Thira (Santorini), Greece, Bodrum, Turkey, Kusadasi (Ephesus), Turkey, Istanbul, Turkey, Cruising the Dardanelles, Piraeus (Athens), Greece, Nafplion, Greece, Istanbul, Turkey, Kusadasi (Ephesus), Turkey, Thira (Santorini), Greece, Rhodes, Greece, Souda (Chania), Greece, Piraeus (Athens), Greece
2026 Sails: Sep 23, More...
19 Night - Cruise & Rail : Slovenia, Venice, Istanbul & the BalkansStarting in Ljubljana, Ljubljana (Lake Bled), Ljubljana (Karst), Transfer to Venice, Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Pula, Rijeka, Sarajevo, Mostar, Belgrade, Sofia, Plovdiv, Istanbul
2026 Sails: Sep 24, 2027: Apr 29, More...
11 Night - Mediterranean with Greek Isles & TurkeyStarting in Athens (Piraeus), Greece, Santorini, Greece, Kusadasi, Turkey (for Ephesus), Istanbul, Turkey, Rhodes, Greece, Sicily (Messina), Italy, Valletta, Malta, Civitavecchia (for Rome), Italy
2026 Sails: Sep 25, More...
61 Night - Western Mediterranean from Southampton to Santa Cruz de TenerifeStarting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife
2026 Sails: Sep 30, More...
50 Night - Western Mediterranean from Southampton to Athens (Piraeus)Starting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Sep 30, More...
71 Night - Cruise Roundtrip from SouthamptonStarting in Southampton, Vigo, Cadiz, Malaga, Melilla, Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Pass Mount Athos, Cruising Sithonia Coastline, Thessaloniki, Mytilene, Kos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Valletta, Trapani, Cartagena ES, Gibraltar, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Sep 30, More...
11 Night - Greece & Turkey Cruise : Athens, Istanbul & SyrosStarting in Athens (Piraeus), Chios, Istanbul, Canakkale (Kepez), Thessaloniki, Volos, Syros, Patmos, Nafplio, Athens (Piraeus)
2026 Sails: Oct 3, More...
