Grand Cayman Island Cruises
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
6 Night - Grand Cayman, Mexico & Bahamas
Starting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Dec 13, More...
7 Night - Bahamas, Mexico & Cayman
Starting in Miami, Florida, Nassau, Bahamas, George Town, Grand Cayman, Cozumel, Mexico, Puerto Costa Maya, Mexico, Miami, Florida
2026 Sails: Dec 13, 2027: Jan 3, Feb 14, Mar 7, Mar 28, More...
21 Night - Caribbean Celebration
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Miami, FL, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, FL
2026 Sails: Dec 17, More...33 Night - Caribbean Celebration
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Miami, FL, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, FL, Praia da Vitoria, Azores, Portugal, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Dec 17, More...
8 Night - Western Caribbean
Starting in Galveston, Tx, Cozumel, Mexico, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Galveston, Tx
2026 Sails: Dec 19, More...
7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Montego Bay, Jamaica, New Orleans, Louisiana
2026 Sails: Dec 19, 2027: Feb 13, More...
21 Night - The Americas & Caribbean
Starting in Fort Lauderdale, St Thomas, Virgin Gorda, St Johns, San Juan, Samana, Nassau (Paradise Island), Fort Lauderdale, Cozumel, Quintana Roo, Belize City, Santo Tomas, Roatan Island, George Town (Grand Cayman), Ocho Rios, Jamaica, Nassau (Paradise Island), Fort Lauderdale
2026 Sails: Dec 20, More...
7 Night - Western Caribbean Holiday
Starting in Miami, Florida, Bimini, Bahamas, George Town, Grand Cayman, Ocho Rios, Jamaica, Falmouth, Jamaica, Miami, Florida
2026 Sails: Dec 20, More...
8 Night - Western Caribbean Holiday Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Belize City, Belize, Puerto Costa Maya, Mexico, George Town, Grand Cayman, Tampa, Florida
2026 Sails: Dec 20, More...
5 Night - Western Caribbean
Starting in Tampa, Fl, Grand Cayman, Cayman Islands, Cozumel, Mexico, Tampa, Fl
2026 Sails: Dec 21, 2027: Jan 4, Feb 1, Mar 15, Mar 29, Apr 26, May 1, Nov 22, Dec 6, Dec 24, Dec 29, 2028: Jan 3, Jan 17, Jan 31, Feb 14, Feb 28, Mar 13, Mar 27, Apr 10, Apr 15, More...
Cruises that visit Caribbean: Cayman Islands: Grand Cayman Island
Click on a cruise ship itinerary that visits Grand Cayman Island (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Grand Cayman Island), please visit: Cruise Search or try our Virtual Cruise Advisor™.
6 Night - Grand Cayman, Mexico & BahamasStarting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Dec 13, More...
7 Night - Bahamas, Mexico & CaymanStarting in Miami, Florida, Nassau, Bahamas, George Town, Grand Cayman, Cozumel, Mexico, Puerto Costa Maya, Mexico, Miami, Florida
2026 Sails: Dec 13, 2027: Jan 3, Feb 14, Mar 7, Mar 28, More...
Deal link -> Special
21 Night - Caribbean CelebrationStarting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Miami, FL, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, FL
2026 Sails: Dec 17, More...
Deal link -> Special
33 Night - Caribbean CelebrationStarting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Miami, FL, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, FL, Praia da Vitoria, Azores, Portugal, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Dec 17, More...
8 Night - Western CaribbeanStarting in Galveston, Tx, Cozumel, Mexico, Grand Cayman, Cayman Islands, Montego Bay, Jamaica, Galveston, Tx
2026 Sails: Dec 19, More...
Deal link -> Special
7 Night - Western Caribbean CruiseStarting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Montego Bay, Jamaica, New Orleans, Louisiana
2026 Sails: Dec 19, 2027: Feb 13, More...
21 Night - The Americas & CaribbeanStarting in Fort Lauderdale, St Thomas, Virgin Gorda, St Johns, San Juan, Samana, Nassau (Paradise Island), Fort Lauderdale, Cozumel, Quintana Roo, Belize City, Santo Tomas, Roatan Island, George Town (Grand Cayman), Ocho Rios, Jamaica, Nassau (Paradise Island), Fort Lauderdale
2026 Sails: Dec 20, More...
Deal link -> Special
7 Night - Western Caribbean HolidayStarting in Miami, Florida, Bimini, Bahamas, George Town, Grand Cayman, Ocho Rios, Jamaica, Falmouth, Jamaica, Miami, Florida
2026 Sails: Dec 20, More...
Deal link -> Special
8 Night - Western Caribbean Holiday CruiseStarting in Tampa, Florida, Cozumel, Mexico, Belize City, Belize, Puerto Costa Maya, Mexico, George Town, Grand Cayman, Tampa, Florida
2026 Sails: Dec 20, More...
5 Night - Western CaribbeanStarting in Tampa, Fl, Grand Cayman, Cayman Islands, Cozumel, Mexico, Tampa, Fl
2026 Sails: Dec 21, 2027: Jan 4, Feb 1, Mar 15, Mar 29, Apr 26, May 1, Nov 22, Dec 6, Dec 24, Dec 29, 2028: Jan 3, Jan 17, Jan 31, Feb 14, Feb 28, Mar 13, Mar 27, Apr 10, Apr 15, More...
