Darien Cruises
Cruises that visit Central America: Panama: Darien
7 Night - The Panama Canal, Pearl Islands and Darien Jungle
Starting in Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Playa Muerto, Darien National Park, Punta Patino Nature Reserve, Balboa / Disembark Ship / Panama City, Panama
2026 Sails: Dec 6, 2028: Mar 9, More...
10 Night - Secrets of Central America
Starting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2026 Sails: Dec 8, 2027: Jan 4, Mar 29, More...10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Dec 18, More...
10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Dec 19, More...10 Night - Secrets of Central America
Starting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2027 Sails: Jan 5, More...7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Portobelo, Crossing the Panama Canal, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Jan 15, More...7 Night - Panama and Costa Rica by Sea : the Natural Wonders of Central America - with Smithsonian Journeys
Starting in Puntarenas, Quepos, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2027 Sails: Feb 19, More...7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...7 Night - Central America Jewels & Panama Canal
Starting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2027 Sails: Mar 5, More...
13 Night - Ancient Kingdoms and Natural Treasures : Chile to Panama
Starting in Valparaiso, Chile, Pinguino de Humboldt National Reserve, At Sea / Paracas, Peru, Paracas, Peru, Salaverry, Peru, Manta, Ecuador, Utria National Park / Ensenada de Utria, Colombia, Darien National Park / Playa del Muerto, Panama, Panama City, Panama
2027 Sails: Mar 21, More...
Cruises that visit Central America: Panama: Darien
Click on a cruise ship itinerary that visits Darien (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Darien), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - The Panama Canal, Pearl Islands and Darien JungleStarting in Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Playa Muerto, Darien National Park, Punta Patino Nature Reserve, Balboa / Disembark Ship / Panama City, Panama
2026 Sails: Dec 6, 2028: Mar 9, More...
10 Night - Secrets of Central AmericaStarting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2026 Sails: Dec 8, 2027: Jan 4, Mar 29, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Dec 18, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Dec 19, More...
10 Night - Secrets of Central AmericaStarting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2027 Sails: Jan 5, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Portobelo, Crossing the Panama Canal, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Jan 15, More...
7 Night - Panama and Costa Rica by Sea : the Natural Wonders of Central America - with Smithsonian JourneysStarting in Puntarenas, Quepos, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2027 Sails: Feb 19, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...
7 Night - Central America Jewels & Panama CanalStarting in Puntarenas, Golfito, Playa Muerto, Darien National Park, Fuerte Amador, Flamenco Island, Crossing the Panama Canal, San Blas Islands, Colon
2027 Sails: Mar 5, More...
13 Night - Ancient Kingdoms and Natural Treasures : Chile to PanamaStarting in Valparaiso, Chile, Pinguino de Humboldt National Reserve, At Sea / Paracas, Peru, Paracas, Peru, Salaverry, Peru, Manta, Ecuador, Utria National Park / Ensenada de Utria, Colombia, Darien National Park / Playa del Muerto, Panama, Panama City, Panama
2027 Sails: Mar 21, More...
