Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
22 Night - Repo - Panama Canal
Starting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Astoria, Or, Victoria CA, Canada, Seattle, Wa
2026 Sails: Apr 11, More...
16 Night - Journeys - Panama Canal
Starting in Mobile, Al, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 12, 2027: Mar 29, More...
6 Night - California (and Mexico) Dreamin
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 12, More...
20 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California, Seattle, Washington
2026 Sails: Apr 13, More...
20 Night - Miami to Seattle
Starting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 14, More...
30 Night - Miami to Seattle
Starting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 14, More...
7 Night - Cabo, Vallarta & Mazatlan
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 17, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 7, Aug 14, Aug 28, Sep 11, More...
7 Night - Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Apr 18, More...
18 Night - Baja Peninsula, Mexican Riviera & Pacific Coast
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California, Victoria CA, Canada, Vancouver, BC, CA
2026 Sails: Apr 18, More...
14 Night - Mexican Riviera & Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2026 Sails: Apr 18, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
22 Night - Repo - Panama CanalStarting in Miami, Fl, Cartagena CO, Panama City, Panama, Transit Panama Canal / At Sea, Panama City, Panama, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Astoria, Or, Victoria CA, Canada, Seattle, Wa
2026 Sails: Apr 11, More...
16 Night - Journeys - Panama CanalStarting in Mobile, Al, Cartagena CO, Panama Canal Transit, Puntarenas, Costa Rica, Cabo San Lucas, Mexico, Seattle, Wa
2026 Sails: Apr 12, 2027: Mar 29, More...
6 Night - California (and Mexico) DreaminStarting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: Apr 12, More...
20 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California, Seattle, Washington
2026 Sails: Apr 13, More...
Deal link -> Special
20 Night - Miami to SeattleStarting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA
2026 Sails: Apr 14, More...
30 Night - Miami to SeattleStarting in Miami, FL, Cartagena CO, Colon, Panama, Transit the Panama Canal, Panama (Full Transit), Puntarenas, Costa Rica, Santa Cruz (for Huatulco), Mexico, Cabo San Lucas, Mexico, Los Angeles, CA, Seattle, WA, Ketchikan, AK, Sitka, AK, Glacier Bay, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Tracy Arm Fjord, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Apr 14, More...
7 Night - Cabo, Vallarta & MazatlanStarting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 17, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 7, Aug 14, Aug 28, Sep 11, More...
7 Night - Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Apr 18, More...
18 Night - Baja Peninsula, Mexican Riviera & Pacific CoastStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California, Victoria CA, Canada, Vancouver, BC, CA
2026 Sails: Apr 18, More...
14 Night - Mexican Riviera & Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2026 Sails: Apr 18, More...