Cabo San Lucas Cruises
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
24 Night - Msc Grand Voyages
Starting in Seattle, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Panama Canal (Transit), Panama, Colon, Panama, Cartagena CO, Miami, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami
2026 Sails: Sep 28, More...
8 Night - Mexican Riviera
Starting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Oct 3, More...
7 Night - Halloween On the High Seas Mexican Riviera Cruise from San Diego
Starting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Oct 3, More...
21 Night - Panama Canal
Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 3, More...
28 Night - Circle Hawaii and Sea of Cortez
Starting in Vancouver, BC, CA, Hilo, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Avalon, California, San Diego, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Oct 3, More...
7 Night - Mexican Riviera
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Oct 3, Oct 10, Oct 17, Oct 24, Oct 31, Nov 7, Nov 14, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, More...
10 Night - Mexican Riviera
Starting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Oct 3, More...
7 Night - Hollywood Sunsets & Mexican Horizons
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Oct 3, Oct 10, More...20 Night - Panama Canal
Starting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 4, More...
Cruises that visit North America: Mexico: Cabo San Lucas
Cruises that depart from Cabo San Lucas
Click on a cruise ship itinerary that visits Cabo San Lucas (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cabo San Lucas), please visit: Cruise Search or try our Virtual Cruise Advisor™.
23 Night - Panama Canal & Pacific CoastStarting in Vancouver, Canada, Victoria CA, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Fort Lauderdale, Florida
2026 Sails: Sep 27, More...
24 Night - Msc Grand VoyagesStarting in Seattle, Los Angeles, San Diego, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Panama Canal (Transit), Panama, Colon, Panama, Cartagena CO, Miami, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami
2026 Sails: Sep 28, More...
8 Night - Mexican RivieraStarting in Long Beach (Los Angeles), Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, La Paz, Mexico, Cabo San Lucas, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Oct 3, More...
7 Night - Halloween On the High Seas Mexican Riviera Cruise from San DiegoStarting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Oct 3, More...
21 Night - Panama CanalStarting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 3, More...
28 Night - Circle Hawaii and Sea of CortezStarting in Vancouver, BC, CA, Hilo, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Avalon, California, San Diego, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Oct 3, More...
7 Night - Mexican RivieraStarting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Oct 3, Oct 10, Oct 17, Oct 24, Oct 31, Nov 7, Nov 14, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, More...
10 Night - Mexican RivieraStarting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Oct 3, More...
7 Night - Hollywood Sunsets & Mexican HorizonsStarting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Oct 3, Oct 10, More...
20 Night - Panama CanalStarting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 4, More...
