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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Suriname : Uruguay



MSC Cruises, MSC Divina
MSC Divina Cruises17 Night - Msc Grand Voyages
Starting in Naples (Pompeii), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Tarragona, Spain, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Oct 29, More...
MSC Cruises, MSC Musica
MSC Musica Cruise Ship13 Night - Msc Grand Voyages
Starting in Tarragona, Spain, Casablanca (Marrakesh), Morocco, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Oct 29, More...
Seabourn Cruise Tours, Seabourn Venture Cruise Tours
Seabourn Venture Cruise Tours21 Night - Brazil, Falklands, Antarctica - Tour N07
Starting in Rio De Janeiro, Brazil, Camboriu, Brazil, Montevideo, Uruguay, The Falkland Islands, Port Stanley, Falkland Islands, The Falkland Islands, Antarctica, Ushuaia, Argentina, Buenos Aires
2026 Sails: Oct 29, More...
Silversea Cruises, Silver Wind
Silver Wind Cruise Ship9 Night - King George Island to Puerto Williams
Starting in King George Island, Antarctic Sound, Antarctic Peninsula, South Shetland Islands, Drake Passage, Puerto Williams
2026 Sails: Oct 29, 2027: Jan 15, Feb 2, Feb 20, Mar 10, Nov 13, Dec 1, Dec 19, 2028: Jan 6, Jan 24, Feb 11, Feb 29, More...
Virgin Voyages, Brilliant Lady
Brilliant Lady Cruises17 Night - Picturesque Panama Canal Collective
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2026 Sails: Oct 29, More...
Holland America Line, Nieuw Amsterdam
Nieuw Amsterdam Cruise Ship21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Oct 30, More...
Lindblad Expeditions Cruise Tours, National Geographic Explorer Cruise Tours
National Geographic Explorer cruise ship20 Night - Antarctica, South Georgia, and the Falklands
Starting in Buenos Aires, Argentina, or Santiago, Chile, Ushuaia, Argentina / EmbarkShip, Antarctica, South Georgia Island, Falkland Islands
2026 Sails: Oct 30, More...
MSC Cruises, MSC Divina
MSC Divina Cruises17 Night - Msc Grand Voyages
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Tarragona, Spain, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Oct 30, More...
MSC Cruises, MSC Divina
MSC Divina Cruises16 Night - Msc Grand Voyages
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Tarragona, Spain, Santa Cruz de Tenerife, Salvador, Brazil, Rio De Janeiro, Brazil
2026 Sails: Oct 30, More...
PONANT, L'Austral
L'Austral Cruises5 Night - Ocean Voyage : Callao - Valparaiso
Starting in Callao, Valparaiso
2026 Sails: Oct 30, More...

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South America Cruises