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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : Uruguay



MSC Cruises, MSC Musica
MSC Musica7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Brazil
2026 Sails: Dec 20, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Santos (Sao Paulo), Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil
2026 Sails: Dec 20, Dec 27, More...
PONANT, Le Boreal
Le Boreal17 Night - The Great Austral Loop
Starting in Ushuaia, Grave Cove, New Island, South Georgia, Antarctic Peninsula, Crossing the Drake Passage, Ushuaia
2026 Sails: Dec 20, 2027: Feb 15, More...
MSC Cruises, MSC Divina
MSC Divina5 Night - South America
Starting in Santos (Sao Paulo), Brazil, Ilha Grande, Brazil, Buzios, Brazil, Ilhabela, Brazil, Santos (Sao Paulo), Brazil
2026 Sails: Dec 21, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - South America
Starting in Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Santos (Sao Paulo), Brazil, Camboriu, Brazil
2026 Sails: Dec 21, Dec 28, More...
Norwegian Cruise Line, Norwegian Sun
Norwegian Sun12 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Miami, Fl
2026 Sails: Dec 21, 2027: Jan 25, Mar 1, More...
Silversea, Silver Dawn
Silver Dawn18 Night - Miami to Los Angeles
Starting in Miami, Fl, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, Jalisco, San Diego, California, Los Angeles, California
2026 Sails: Dec 21, More...
Silversea, Silver Dawn
Silver Dawn40 Night - Cruise from Miami to Papeete
Starting in Miami, Cartagena CO, Panama Canal Transit, Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, Los Angeles, Nawiliwili, Kahului, Hilo, Honolulu, Nuku Hiva, Rangiroa, Moorea Island, Raiatea, Papeete
2026 Sails: Dec 21, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - South America
Starting in Rio De Janeiro, Brazil, Ilha Grande, Brazil, Buzios, Brazil, Paranagua, Brazil, Itajai, Brazil, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, 2027: Jan 26, More...
MSC Cruises, MSC Splendida
MSC Splendida9 Night - South America
Starting in Rio De Janeiro, Brazil, Ilhabela, Brazil, Camboriu, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Ilhabela, Brazil, Rio De Janeiro, Brazil
2026 Sails: Dec 22, More...

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South America Cruises