Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
10 Night - Best of Italy & Croatia
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Bari, Italy, Dubrovnik, Croatia, Split, Croatia, Ravenna, Italy
2028 Sails: Apr 28, May 19, Jun 9, Jun 30, Jul 21, Aug 11, Sep 22, More...
10 Night - Spain Intensive Cruise : Palma, Malaga & Seville
Starting in Rome (Civitavecchia), Olbia, Sardinia, Mahon, Menorca, Palma, Majorca, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon
2028 Sails: Apr 29, More...21 Night - Spain, Portugal & France Combination Cruise : Seville, Lisbon & Normandy
Starting in Rome (Civitavecchia), Olbia, Sardinia, Mahon, Menorca, Palma, Majorca, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon, Porto (Leixoes), La Coruna, Gijon, Spain, Bilbao, Bordeaux, Saint-malo, Cherbourg, Portsmouth UK
2028 Sails: Apr 29, More...
7 Night - Enchanting Italian Coastlines
Starting in Rome (Civitavecchia), Italy, Amalfi, Italy / Capri, Italy, Capri, Italy / Sorrento, Italy, Sorrento, Italy, Gaeta, Italy, Porto Cervo, Sardinia, Italy, Bonifacio, Corsica, France, Rome (Civitavecchia), Italy
2028 Sails: Apr 30, More...
11 Night - Italy, Greek Isles & Malta
Starting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Valletta, Malta, Ephesus (Kusadasi), Turkey, Santorini, Greece, Athens (Piraeus), Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2028 Sails: May 1, More...
10 Night - Italy Circumnavigation
Starting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Cruising the Ionian Sea, Igoumenitsa, Montenegro, Dubrovnik, Croatia, Split, Zadar, Trieste
2028 Sails: May 1, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)
Starting in Rome (Civitavecchia), Sorrento, Lipari, Taormina (Naxos), Sicily, Chania (Souda), Crete, Milos, Athens (Piraeus)
2028 Sails: May 2, More...
7 Night - Amalfi Coast, Africa & Iberia
Starting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2028 Sails: May 2, Jun 27, 2029: Apr 14, More...
7 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Olympia (Katakolon), Greece, Corfu, Greece, Zadar, Croatia, Ravenna, Italy
2028 Sails: May 6, More...
11 Night - Italy, Portugal & Morocco
Starting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Cagliari, Sardinia, Italy, Malaga, Spain, Tangier, Morocco, Casablanca, Morocco, Madeira (Funchal), Portugal, Porto (Leixoes), Portugal, Lisbon, Portugal
2028 Sails: May 8, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Deal link -> Special
10 Night - Best of Italy & CroatiaStarting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Bari, Italy, Dubrovnik, Croatia, Split, Croatia, Ravenna, Italy
2028 Sails: Apr 28, May 19, Jun 9, Jun 30, Jul 21, Aug 11, Sep 22, More...
Deal link -> Special
10 Night - Spain Intensive Cruise : Palma, Malaga & SevilleStarting in Rome (Civitavecchia), Olbia, Sardinia, Mahon, Menorca, Palma, Majorca, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon
2028 Sails: Apr 29, More...
Deal link -> Special
21 Night - Spain, Portugal & France Combination Cruise : Seville, Lisbon & NormandyStarting in Rome (Civitavecchia), Olbia, Sardinia, Mahon, Menorca, Palma, Majorca, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon, Porto (Leixoes), La Coruna, Gijon, Spain, Bilbao, Bordeaux, Saint-malo, Cherbourg, Portsmouth UK
2028 Sails: Apr 29, More...
7 Night - Enchanting Italian CoastlinesStarting in Rome (Civitavecchia), Italy, Amalfi, Italy / Capri, Italy, Capri, Italy / Sorrento, Italy, Sorrento, Italy, Gaeta, Italy, Porto Cervo, Sardinia, Italy, Bonifacio, Corsica, France, Rome (Civitavecchia), Italy
2028 Sails: Apr 30, More...
11 Night - Italy, Greek Isles & MaltaStarting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Valletta, Malta, Ephesus (Kusadasi), Turkey, Santorini, Greece, Athens (Piraeus), Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2028 Sails: May 1, More...
10 Night - Italy CircumnavigationStarting in Rome (Civitavecchia), Salerno, Messina (Sicily), Valletta, Cruising the Ionian Sea, Igoumenitsa, Montenegro, Dubrovnik, Croatia, Split, Zadar, Trieste
2028 Sails: May 1, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)Starting in Rome (Civitavecchia), Sorrento, Lipari, Taormina (Naxos), Sicily, Chania (Souda), Crete, Milos, Athens (Piraeus)
2028 Sails: May 2, More...
7 Night - Amalfi Coast, Africa & IberiaStarting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2028 Sails: May 2, Jun 27, 2029: Apr 14, More...
7 Night - Italy, Greece & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Olympia (Katakolon), Greece, Corfu, Greece, Zadar, Croatia, Ravenna, Italy
2028 Sails: May 6, More...
11 Night - Italy, Portugal & MoroccoStarting in Rome (Civitavecchia), Italy, Sicily (Palermo), Italy, Cagliari, Sardinia, Italy, Malaga, Spain, Tangier, Morocco, Casablanca, Morocco, Madeira (Funchal), Portugal, Porto (Leixoes), Portugal, Lisbon, Portugal
2028 Sails: May 8, More...
