Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
9 Night - Fountains to Flamenco
Starting in Rome (Civitavecchia), Salerno, Olbia / Porto Cervo (Sardinia), Ajaccio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Provence (Marseille), Ibiza, Palma De Mallorca, Barcelona
2027 Sails: Nov 9, More...
14 Night - Spain, Portugal & the Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2027 Sails: Nov 9, 2028: Apr 4, More...
7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona (Tarragona), Barcelona
2027 Sails: Nov 14, More...
15 Night - Mediterranean Pilgrimage
Starting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, La Goulette, Cagliari (Sardinia), Cruising the Mediterranean Sea, Palma De Mallorca, Barcelona, Palamos, Provence (Marseille), Tuscany (Livorno), Cruising the Mediterranean Sea, Alicante, Valencia, Barcelona
2027 Sails: Nov 20, More...8 Night - Knights & Sunsets
Starting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, La Goulette, Cagliari (Sardinia), Cruising the Mediterranean Sea, Palma De Mallorca, Barcelona
2027 Sails: Nov 20, More...
7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Nov 21, More...
14 Night - Spain, Portugal & the Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2027 Sails: Nov 24, 2028: Mar 23, More...
12 Night - Historic Harbors
Starting in Rome (Civitavecchia), Palermo (Sicily), Catania (Sicily), Katakolon, Heraklion (Crete), Rhodes, Limassol, Alexandria EG, Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Nov 26, More...
23 Night - Old & New Worlds
Starting in Rome (Civitavecchia), Bonifacio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Toulon, Barcelona, Valencia, Gibraltar, Seville (Cadiz), Lisbon, Santa Cruz de Tenerife, Funchal (Madeira), Ponta Delgada (Azores), Horta (Azores), Miami
2027 Sails: Nov 27, More...10 Night - Roman Holiday
Starting in Rome (Civitavecchia), Bonifacio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Toulon, Barcelona, Valencia, Gibraltar, Seville (Cadiz), Lisbon
2027 Sails: Nov 27, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Deal link -> Special
9 Night - Fountains to FlamencoStarting in Rome (Civitavecchia), Salerno, Olbia / Porto Cervo (Sardinia), Ajaccio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Provence (Marseille), Ibiza, Palma De Mallorca, Barcelona
2027 Sails: Nov 9, More...
14 Night - Spain, Portugal & the MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2027 Sails: Nov 9, 2028: Apr 4, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona (Tarragona), Barcelona
2027 Sails: Nov 14, More...
15 Night - Mediterranean PilgrimageStarting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, La Goulette, Cagliari (Sardinia), Cruising the Mediterranean Sea, Palma De Mallorca, Barcelona, Palamos, Provence (Marseille), Tuscany (Livorno), Cruising the Mediterranean Sea, Alicante, Valencia, Barcelona
2027 Sails: Nov 20, More...
8 Night - Knights & SunsetsStarting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, La Goulette, Cagliari (Sardinia), Cruising the Mediterranean Sea, Palma De Mallorca, Barcelona
2027 Sails: Nov 20, More...
7 Night - Journey to AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Nov 21, More...
14 Night - Spain, Portugal & the MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2027 Sails: Nov 24, 2028: Mar 23, More...
12 Night - Historic HarborsStarting in Rome (Civitavecchia), Palermo (Sicily), Catania (Sicily), Katakolon, Heraklion (Crete), Rhodes, Limassol, Alexandria EG, Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Nov 26, More...
23 Night - Old & New WorldsStarting in Rome (Civitavecchia), Bonifacio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Toulon, Barcelona, Valencia, Gibraltar, Seville (Cadiz), Lisbon, Santa Cruz de Tenerife, Funchal (Madeira), Ponta Delgada (Azores), Horta (Azores), Miami
2027 Sails: Nov 27, More...
10 Night - Roman HolidayStarting in Rome (Civitavecchia), Bonifacio (Corsica), Florence / Pisa / Tuscany (Livorno), Cannes, Toulon, Barcelona, Valencia, Gibraltar, Seville (Cadiz), Lisbon
2027 Sails: Nov 27, More...
