Rome Cruise Departures

Cruises that depart from Mediterranean: Italy: Rome

Cruises that visit Rome

See all River Cruises that depart from Rome

Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.

10 Night - Eastbound Adventure
Starting in Rome (Civitavecchia), Sorrento / Capri, Catania (Sicily), Valletta, Gythion, Milos, Nafplion, Athens (Piraeus), Canakkale (Troy), Istanbul
2027 Sails: Oct 18, More...

Royal Caribbean, Explorer of the Seas

7 Night - Best of Greece Cruise
Starting in Rome (Civitavecchia), Italy, Olympia (Katakolon), Greece, Chania (Souda), Crete, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Santorini, Greece, Athens (Piraeus), Greece
2027 Sails: Oct 18, More...

Oceania Cruises, Oceania Allura

7 Night - Riviera Radiance
Starting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Cinque Terre (La Spezia), Cannes, Provence (Marseille), Palma De Mallorca, Valencia, Barcelona (Tarragona)
2027 Sails: Oct 22, More...

Viking Ocean, Viking Libra

14 Night - Spain, Portugal & the Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona (Tarragona), Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2027 Sails: Oct 24, More...

Viking Ocean, Viking Libra

7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona (Tarragona)
2027 Sails: Oct 24, More...

Royal Caribbean, Legend of the Seas

3 Night - Western Mediterranean Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain
2027 Sails: Oct 28, More...

Celebrity Cruises, Celebrity Ascent

14 Night - Italy & Portugal Transatlantic
Starting in Rome (Civitavecchia), Italy, Cagliari, Sardinia, Italy, Gibraltar, United Kingdom, Madeira (Funchal), Portugal, Royal Naval Dockyard, Bermuda, Fort Lauderdale, Florida
2027 Sails: Oct 29, More...

Celebrity Cruises, Celebrity Constellation

Deal link -> Special

16 Night - Spain & Morocco Transatlantic
Starting in Rome (Civitavecchia), Italy, Alicante, Spain, Malaga, Spain, Gibraltar, United Kingdom, Casablanca, Morocco, Tampa, Florida
2027 Sails: Oct 29, More...

Viking Ocean, Viking Neptune

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Chioggia)
2027 Sails: Oct 30, More...

Regent Seven Seas, Seven Seas Splendor

7 Night - Spellbinding Mediterranean
Starting in Rome (Civitavecchia), La Spezia (Cinque Terre), Provence (Marseille), Palamos, Cruising the Mediterranean Sea, Malaga, Gibraltar, Lisbon
2027 Sails: Oct 31, More...

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