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Puerto Rico Cruise Departures

Cruises that depart from Caribbean: Puerto Rico

Cruises that visit Puerto Rico

Click on a cruise ship itinerary sailing from Puerto Rico (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Puerto Rico), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: San Juan

Departing from
Puerto Rico
Cruise Specials

Explora Journeys, EXPLORA I
EXPLORA I Cruises7 Night - A Journey Into Tropical Utopia & Spanish Legacy with Art Deco Flair
Starting in San Juan, St Johns AG, Antigua, Road Bay, Spanish Town (Virgin Gorda), Charlotte Amalie (Saint Thomas), Miami
2026 Sails: Mar 2, More...
Explora Journeys, EXPLORA I
EXPLORA I Cruises23 Night - A Grand Journey of Lively Latin Flair, Modern Marvels & Coastal Charm
Starting in San Juan, St Johns AG, Antigua, Road Bay, Spanish Town (Virgin Gorda), Charlotte Amalie (Saint Thomas), Miami, San Juan, St Maarten / Philipsburg, Santa Cruz de Tenerife, Arrecife (Lanzarote), Tangier, Barcelona
2026 Sails: Mar 2, More...
Ritz-Carlton Yacht Collection, Evrima
Evrima Cruises6 Night - San Juan / San Juan
Starting in San Juan, St Johns AG, Gustavia, Virgin Gorda, St John VI, San Juan
2026 Sails: Mar 2, More...
Explora Journeys, EXPLORA II
EXPLORA II Cruises15 Night - An Extended Journey Through Spectacular Nature and Historic Wonders
Starting in San Juan, St Georges, Grenada, Bequia, Bridgetown, Fort-de-France, Martinique, Gustavia, Basseterre, San Juan, Road Bay, St Johns AG, Antigua, St Maarten / Philipsburg, Spanish Town (Virgin Gorda), Miami
2026 Sails: Mar 3, More...
EXPLORA II Cruises8 Night - A Journey from San Juan to San Juan
Starting in San Juan, St Georges, Grenada, Bequia, Bridgetown, Fort-de-France, Martinique, Gustavia, Basseterre, San Juan
2026 Sails: Mar 3, More...
Ritz-Carlton Yacht Collection, Ilma
Ilma Cruises8 Night - San Juan / San Juan
Starting in San Juan, Bequia, St Georges, Soufriere, Portsmouth DM, Falmouth Harbour, Antigua, Virgin Gorda, San Juan
2026 Sails: Mar 6, More...
Windstar Cruises, Star Seeker
Star Seeker Cruises14 Night - Star Collector : Lovely Leewards
Starting in San Juan, St John VI (Cruz Bay), US Virgin Islands, Basseterre, Gustavia, Philipsburg, St Maarten, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, San Juan, Marigot, St Martin, Les Saintes, Mayreau, Bequia, Pigeon Island, The Pitons, San Juan
2026 Sails: Mar 6, More...
Virgin Voyages, Valiant Lady
Valiant Lady Cruises7 Night - Quaint Castries to Elegant Antigua
Starting in San Juan, Puerto Rico, Basseterre, Saint Kitts and Nevis, Castries, Saint Lucia, Fort-De-France, Martinique, St Johns AG, Antigua and Barbuda, Road Town, Tortola, British Virgin Islands, San Juan, Puerto Rico
2026 Sails: Mar 7, More...
Princess Cruises, Grand Princess
Grand Princess Cruise Ship14 Night - Southern Caribbean Adventurer
Starting in San Juan, Puerto Rico, St Thomas, US Virgin Islands, St Maarten, Antigua, Dominica, Barbados, San Juan, Puerto Rico, Tortola, British Virgin Islands, St Kitts, Dominica, Grenada, Barbados, San Juan, Puerto Rico
2026 Sails: Mar 8, More...
Ritz-Carlton Yacht Collection, Evrima
Evrima Cruises4 Night - San Juan / San Juan
Starting in San Juan, St John VI, Gustavia, Virgin Gorda, San Juan
2026 Sails: Mar 8, More...

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Puerto Rico Cruise Departures