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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Windstar, Wind Surf
Wind Surf17 Night - Star Collector : Italian Charms & Croatian Coastlines
Starting in Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice, Rovinj, Zadar, Hvar, Kotor, Dubrovnik, Croatia, Piran, Venice
2026 Sails: Aug 1, More...
Azamara Onward11 Night - Solar Eclipse Cruise : Greece, Turkey & Italy
Starting in Athens (Piraeus), Ephesus (Kusadasi), Heraklion, (Crete), Taormina (Giardini Naxos), Sicily, Sorrento, Rome (Civitavecchia), Florence / Pisa (Livorno), Nice, Provence (Toulon), Barcelona
2026 Sails: Aug 2, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - Mediterranean
Starting in Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy
2026 Sails: Aug 2, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem7 Night - Europe - Adriatic & Greece - Venice
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Split, Croatia, Corfu, Greece, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Aug 2, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl7 Night - Europe
Starting in Piraeus / Athens, Greece, Santorini Island, Greece, Olympia / Katakolon, Greece, Corfu, Greece, Kotor, Montenegro, Zadar, Croatia, Koper, Slovenia, Venice (Ravenna), Italy
2026 Sails: Aug 2, More...
Seabourn Quest14 Night - Grecian Gems & Dalmatian Delights
Starting in Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Split, Croatia, Vis Island, Croatia, Zadar, Croatia, Dubrovnik, Croatia, Korcula, Croatia, Brindisi (Lecce), Italy, Sarande, Albania, Zakinthos, Greece, Nafplion, Greece, Piraeus (Athens), Greece
2026 Sails: Aug 2, More...
Seabourn Quest7 Night - Jewels of the Dalmatian Coast
Starting in Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Split, Croatia, Vis Island, Croatia, Zadar, Croatia, Dubrovnik, Croatia
2026 Sails: Aug 2, Sep 27, More...
Silversea, Silver Nova
Silver Nova7 Night - Fusina to Athens
Starting in Fusina (Venice), Zadar, Hvar, Dubrovnik, Croatia, Katakolon (Olympia), Gythion, Athens (Piraeus)
2026 Sails: Aug 2, More...
Queen Victoria7 Night - Italy and Adriatic
Starting in Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 3, More...
Cunard Line, Queen Victoria
Queen Victoria14 Night - Adriatic and Western Mediterranean
Starting in Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain
2026 Sails: Aug 3, More...

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Mediterranean Cruise Departures