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Mediterranean Cruise Departures

Cruises that depart from Mediterranean

Cruises that visit Mediterranean

See all River Cruises that depart from Mediterranean

Click on a cruise ship itinerary sailing from Mediterranean (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mediterranean), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Croatia / Hrvatska : Cyprus : Egypt : Greece : Italy : Malta : Monaco : Slovenia : Turkey

Departing from
Mediterranean
Cruise Specials

Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager10 Night - Tuscan Summer
Starting in Rome (Civitavecchia), Tuscany (Livorno), Toulon, Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Malaga, Gibraltar, Cruising the Atlantic Ocean, Portimao, Lisbon
2026 Sails: Jul 10, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa14 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Corfu, Zakynthos, Argostoli (Cephalonia), Montenegro, Rijeka, Marghera (Venice), Bari, Thira (Santorini), Mykonos, Katakolon (Olympia), Marghera (Venice)
2026 Sails: Jul 11, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa7 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Corfu, Zakynthos, Argostoli (Cephalonia), Montenegro, Rijeka, Marghera (Venice)
2026 Sails: Jul 11, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra7 Night - Classical Greece
Starting in Athens (Piraeus), Greece, Delos, Greece / Mykonos, Greece, Bodrum, Turkey, Rhodes, Greece, Santorini, Greece, Chania, Greece, Hydra, Greece, Athens (Piraeus), Greece
2026 Sails: Jul 11, Jul 25, Aug 22, Sep 5, More...
Emerald Cruises, Emerald Kaia
Emerald Kaia7 Night - Croatian Coast and the Best of the Adriatic
Starting in Venice, Italy, Rovinj, Croatia, Sibenik, Croatia, Trogir, Croatia, Vis / Hvar, Croatia, Hvar, Croatia, Korcula, Croatia, Dubrovnik, Croatia
2026 Sails: Jul 11, Aug 1, Aug 15, More...
Princess Cruises, Sun Princess
Sun Princess7 Night - Mediterranean with Greece & Adriatic
Starting in Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Jul 11, Aug 1, Aug 22, Sep 12, 2027: Apr 25, May 16, Sep 19, Oct 10, Oct 31, More...
Ritz-Carlton, Ilma
Ilma7 Night - Athens (Lavrion) / Venice
Starting in Athens (Lavrion), Corfu, Kotor, Dubrovnik, Croatia, Hvar, Zadar, Venice
2026 Sails: Jul 11, More...
Royal Caribbean, Legend of the Seas
Legend of the Seas7 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 11, More...
Star Clippers, Star Flyer
Star Flyer7 Night - Northern Cyclades
Starting in Piraeus (Port of Athens), Greece, Morning Sailing Through Samos Strait, Kusadasi, Turkey (Optional Tour Ephesus), Patmos, Greece, Amorgos, Greece, Mykonos, Greece, Sifnos, Greece, Piraeus (Port of Athens), Greece
2026 Sails: Jul 11, Aug 1, Aug 22, Sep 12, More...

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Mediterranean Cruise Departures